| Literature DB >> 27330038 |
Yingdan Chen1, Songchao Yin1, Meirong Li1, Rongzhang Chen1, Ling Wei1, Han Ma1, Shuwen Deng2, Gert Sybren de Hoog2,3,4,5, Wei Lai1, Chun Lu6, Peiying Feng7.
Abstract
A first auricular case of chromoblastomycosis due to Fonsecaea nubica is reported in a 42-year-old Chinese male. He presented a slightly verrucous, erythematous plaque on his right auricle which had gradually extended over a 10-year period, and the patient reported a history of dog flea sting before onset of the lesions. Diagnosis was based on histopathological and mycological examination of clinical samples, which revealed muriform cells. Identification of the aetiological agent was assessed by morphological characteristics and confirmed at species level by sequencing of the rDNA internal transcribed spacer (ITS). The patient showed marked clinical improvement after 3 months combination therapy with itraconazole and terbinafine. The possible mode of transmission of auricular chromoblastomycosis is discussed.Entities:
Keywords: Fonsecaea nubica; auricle; chromoblastomycosis; internal transcribed spacer rDNA
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Year: 2016 PMID: 27330038 DOI: 10.1111/myc.12523
Source DB: PubMed Journal: Mycoses ISSN: 0933-7407 Impact factor: 4.377