| Literature DB >> 27329427 |
Flavia Feier1,2, Eduardo A da Fonseca1,2, Helry L Candido1,2, Renata Pugliese1,2, Marcel R Benavides1,2, Romerito Neiva1,2, Paulo Chapchap1, Joao Seda-Neto1,2.
Abstract
Re-LT is the only recourse for patients with liver graft failure. However, survival rates after re-LT are lower than those of primary transplants. Few reports are available regarding re-LT with LDs in children. The objective of this study was to describe our cohort of patients retransplanted with LD and emphasize the technical aspects of a re-LT with LD. This is a retrospective report of a series of 18 children (<18 yr old) submitted to 20 re-LT from January 1997 to December 2013 at Hospital Sirio-Libanes and Hospital AC Camargo Cancer Center. The one- and five-yr survival for patients retransplanted with LD was 70.6% and 58.6%. Little technical modifications from a regular LD primary transplant were needed in patients retransplanted with LD. Seven (38.8%) patients presented vascular complications following re-LT and three presented biliary complications (16.6%). In conclusion, a re-LT with LD is an acceptable alternative for children who experience liver graft failure and it does not compromise the donor pool. Further experience with re-LT with LD may support this therapy.Entities:
Keywords: graft; liver; outcomes; pediatric; transplantation
Mesh:
Year: 2016 PMID: 27329427 DOI: 10.1111/petr.12735
Source DB: PubMed Journal: Pediatr Transplant ISSN: 1397-3142