| Literature DB >> 27328556 |
Stefani Madison, Elizabeth Aubrey Brown, Rachel Franklin, Elizabeth A Wickersham, Laine H McCarthy.
Abstract
CLINICAL QUESTION: In pediatric populations, is nasal saline irrigation as effective as intranasal corticosteroids at relieving allergic rhinitis symptoms? ANSWER: No. Intranasal steroids are more effective than nasal saline alone to reduce symptoms of allergic rhinitis (AR) in children. Combination therapy further improves symptom reduction. LEVEL OF EVIDENCE FOR THE ANSWER: B SEARCH TERMS: Allergic Rhinitis, Nasal Saline, Nasal corticosteroids, children younger than age 18. DATE SEARCH WAS CONDUCTED: August and September 2014, October 2015. INCLUSION CRITERIA: Meta-analyses, randomized controlled trials, systematic reviews, cohort studies, nasal spray, hypertonic saline solution, nasal lavage, rhinitis, intranasal administration, nasal saline, human, English language. EXCLUSION CRITERIA: Antihistamines, Adults, Articles older than 2008.Entities:
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Year: 2016 PMID： 27328556 PMCID： PMC4918463
Source DB: PubMed Journal: J Okla State Med Assoc ISSN： 0030-1876