Literature DB >> 2732834

Giant cell reaction to ameloblastoma: an immunohistochemical and ultrastructural study of a case.

T Kawakami1, M Antoh, T Minemura.   

Abstract

Histopathologic, immunohistochemical, and ultrastructural features of the giant cells appearing in the tissue surrounding an ameloblastoma are presented. These giant cells exhibited strong activity of a highly stable form of acid phosphatase, and were positive for alpha-1-antichymotrypsin. Ultrastructurally, the cytoplasm of the giant cells contained numerous mitochondria, and the cell membrane was comparatively smooth. Therefore, it is proposed that these multinucleated giant cells are reactive to the invasion of ameloblastoma and are histiocytic in origin.

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Year:  1989        PMID： 2732834     DOI： 10.1016/s0278-2391(89)80017-5

Source DB:  PubMed          Journal:  J Oral Maxillofac Surg        ISSN： 0278-2391            Impact factor:   1.895


  5 in total

Review 1.  Hybrid Central Odontogenic Fibroma with Giant Cell Granuloma like Lesion: A Report of Three Additional Cases and Review of the Literature.

Authors:  Jasbir D Upadhyaya; Donald M Cohen; Mohammed N Islam; Indraneel Bhattacharyya
Journal:  Head Neck Pathol       Date:  2017-08-07

2.  So-called hybrid central odontogenic fibroma/central giant cell lesion of the jaws. A report on seven additional cases, including an example in a patient with cherubism, and hypotheses on the pathogenesis.

Authors:  Konstantinos I Tosios; Rajaram Gopalakrishnan; Ioannis G Koutlas
Journal:  Head Neck Pathol       Date:  2008-08-23

3.  Clinicopathologic and Molecular Characteristics of Familial Cherubism with Associated Odontogenic Tumorous Proliferations.

Authors:  Prokopios P Argyris; Rajaram Gopalakrishnan; Ying Hu; Ernst J Reichenberger; Ioannis G Koutlas
Journal:  Head Neck Pathol       Date:  2017-07-18

4.  Central Odontogenic Fibroma with Giant Cell Granuloma-Like Lesion: A Report of an Additional Case and Review of Literature.

Authors:  Omneya R Ramadan; Marwa M Essawy
Journal:  Head Neck Pathol       Date:  2020-03-24

5.  A peripheral giant cell granuloma with extensive osseous metaplasia or a hybrid peripheral giant cell granuloma-peripheral ossifying fibroma: a case report.

Authors:  Ezinne I Ogbureke; Nadarajah Vigneswaran; Matthew Seals; Gary Frey; Cleverick D Johnson; Kalu U E Ogbureke
Journal:  J Med Case Rep       Date:  2015-02-04
  5 in total

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