Literature DB >> 27327378

Incorporation and visualization of azido-functionalized N-oleoyl serinol in Jurkat cells, mouse brain astrocytes, 3T3 fibroblasts and human brain microvascular endothelial cells.

T Walter1, L Collenburg2, L Japtok3, B Kleuser3, S Schneider-Schaulies2, N Müller2, J Becam4, A Schubert-Unkmeir4, J N Kong5, E Bieberich5, J Seibel1.   

Abstract

The synthesis and biological evaluation of azido-N-oleoyl serinol is reported. It mimicks biofunctional lipid ceramides and has shown to be capable of click reactions for cell membrane imaging in Jurkat and human brain microvascular endothelial cells.

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Year:  2016        PMID： 27327378      PMCID： PMC4947872          DOI： 10.1039/c6cc02879a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  18 in total

1.  Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate.

Authors:  O Cuvillier; G Pirianov; B Kleuser; P G Vanek; O A Coso; S Gutkind; S Spiegel
Journal:  Nature       Date:  1996-06-27       Impact factor: 49.962

2.  Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD).

Authors:  Guanghu Wang; Michael Dinkins; Qian He; Gu Zhu; Christophe Poirier; Andrew Campbell; Margot Mayer-Proschel; Erhard Bieberich
Journal:  J Biol Chem       Date:  2012-04-24       Impact factor: 5.157

3.  Structure of a cell polarity regulator, a complex between atypical PKC and Par6 PB1 domains.

Authors:  Yoshinori Hirano; Sosuke Yoshinaga; Ryu Takeya; Nobuo N Suzuki; Masataka Horiuchi; Motoyuki Kohjima; Hideki Sumimoto; Fuyuhiko Inagaki
Journal:  J Biol Chem       Date:  2004-12-07       Impact factor: 5.157

4.  N-acylated serinol is a novel ceramide mimic inducing apoptosis in neuroblastoma cells.

Authors:  E Bieberich; T Kawaguchi; R K Yu
Journal:  J Biol Chem       Date:  2000-01-07       Impact factor: 5.157

5.  Synthesis and characterization of novel ceramide analogs for induction of apoptosis in human cancer cells.

Authors:  Erhard Bieberich; Bin Hu; Jeane Silva; Sarah MacKinnon; Robert K Yu; Helen Fillmore; William C Broaddus; Raphael M Ottenbrite
Journal:  Cancer Lett       Date:  2002-07-08       Impact factor: 8.679

6.  Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells.

Authors:  Guanghu Wang; Jeane Silva; Kannan Krishnamurthy; Eric Tran; Brian G Condie; Erhard Bieberich
Journal:  J Biol Chem       Date:  2005-05-18       Impact factor: 5.157

7.  Fibronectin mediates Opc-dependent internalization of Neisseria meningitidis in human brain microvascular endothelial cells.

Authors:  Alexandra Unkmeir; Kirsten Latsch; Guido Dietrich; Eva Wintermeyer; Birgitta Schinke; Stefan Schwender; Kwang Sik Kim; Martin Eigenthaler; Matthias Frosch
Journal:  Mol Microbiol       Date:  2002-11       Impact factor: 3.501

8.  A vital stain for the Golgi apparatus.

Authors:  N G Lipsky; R E Pagano
Journal:  Science       Date:  1985-05-10       Impact factor: 47.728

9.  Aging up-regulates expression of inflammatory mediators in mouse adipose tissue.

Authors:  Dayong Wu; Zhihong Ren; Munkyong Pae; Weimin Guo; Xuelin Cui; Alfred H Merrill; Simin Nikbin Meydani
Journal:  J Immunol       Date:  2007-10-01       Impact factor: 5.422

10.  Programmed cell death induced by ceramide.

Authors:  L M Obeid; C M Linardic; L A Karolak; Y A Hannun
Journal:  Science       Date:  1993-03-19       Impact factor: 47.728
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  6 in total

Review 1.  Lysosphingolipids and sphingolipidoses: Psychosine in Krabbe's disease.

Authors:  Stefka Spassieva; Erhard Bieberich
Journal:  J Neurosci Res       Date:  2016-11       Impact factor: 4.164

Review 2.  Sphingolipids and lipid rafts: Novel concepts and methods of analysis.

Authors:  Erhard Bieberich
Journal:  Chem Phys Lipids       Date:  2018-09-05       Impact factor: 3.329

3.  Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes.

Authors:  Ji-Na Kong; Zhihui Zhu; Yutaka Itokazu; Guanghu Wang; Michael B Dinkins; Liansheng Zhong; Hsuan-Pei Lin; Ahmed Elsherbini; Silvia Leanhart; Xue Jiang; Haiyan Qin; Wenbo Zhi; Stefka D Spassieva; Erhard Bieberich
Journal:  J Lipid Res       Date:  2018-01-10       Impact factor: 5.922

4.  Nanoscale imaging of bacterial infections by sphingolipid expansion microscopy.

Authors:  Ralph Götz; Tobias C Kunz; Julian Fink; Franziska Solger; Jan Schlegel; Jürgen Seibel; Vera Kozjak-Pavlovic; Thomas Rudel; Markus Sauer
Journal:  Nat Commun       Date:  2020-12-02       Impact factor: 14.919

5.  Synthesis and Characterization of Ceramide-Containing Liposomes as Membrane Models for Different T Cell Subpopulations.

Authors:  Sascha Eder; Claudia Hollmann; Putri Mandasari; Pia Wittmann; Fabian Schumacher; Burkhard Kleuser; Julian Fink; Jürgen Seibel; Jürgen Schneider-Schaulies; Christian Stigloher; Niklas Beyersdorf; Sofia Dembski
Journal:  J Funct Biomater       Date:  2022-08-02

6.  The Neutral Sphingomyelinase 2 Is Required to Polarize and Sustain T Cell Receptor Signaling.

Authors:  Charlene Börtlein; Annette Draeger; Roman Schoenauer; Alexander Kuhlemann; Markus Sauer; Sibylle Schneider-Schaulies; Elita Avota
Journal:  Front Immunol       Date:  2018-04-18       Impact factor: 7.561
  6 in total

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