Literature DB >> 27324359

The Future of Genetics and Genomics: Closing the Phenotype Gap in Precision Medicine.

Calum A MacRae1, Ramachandran S Vasan2.   

Abstract

Entities:  

Keywords:  genetics; genomics; phenotyping

Mesh：

Year:  2016        PMID： 27324359      PMCID： PMC6188655          DOI： 10.1161/CIRCULATIONAHA.116.022547

Source DB:  PubMed          Journal:  Circulation        ISSN： 0009-7322            Impact factor:   29.690


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  39 in total

1.  Segregation at three loci explains familial and population risk in Hirschsprung disease.

Authors:  Stacey B Gabriel; Rémi Salomon; Anna Pelet; Misha Angrist; Jeanne Amiel; Myriam Fornage; Tania Attié-Bitach; Jane M Olson; Robert Hofstra; Charles Buys; Julie Steffann; Arnold Munnich; Stanislas Lyonnet; Aravinda Chakravarti
Journal:  Nat Genet       Date:  2002-04-15       Impact factor: 38.330

Review 2.  Zebrafish-based small molecule discovery.

Authors:  Calum A MacRae; Randall T Peterson
Journal:  Chem Biol       Date:  2003-10

3.  Mapping a gene for familial hypertrophic cardiomyopathy to chromosome 14q1.

Authors:  J A Jarcho; W McKenna; J A Pare; S D Solomon; R F Holcombe; S Dickie; T Levi; H Donis-Keller; J G Seidman; C E Seidman
Journal:  N Engl J Med       Date:  1989-11-16       Impact factor: 91.245

4.  A genetic study of Hirschsprung disease.

Authors:  J A Badner; W K Sieber; K L Garver; A Chakravarti
Journal:  Am J Hum Genet       Date:  1990-03       Impact factor: 11.025

5.  Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study cohorts.

Authors:  Alexander G Bick; Jason Flannick; Kaoru Ito; Susan Cheng; Ramachandran S Vasan; Michael G Parfenov; Daniel S Herman; Steven R DePalma; Namrata Gupta; Stacey B Gabriel; Birgit H Funke; Heidi L Rehm; Emelia J Benjamin; Jayashri Aragam; Herman A Taylor; Ervin R Fox; Christopher Newton-Cheh; Sekar Kathiresan; Christopher J O'Donnell; James G Wilson; David M Altshuler; Joel N Hirschhorn; J G Seidman; Christine Seidman
Journal:  Am J Hum Genet       Date:  2012-09-07       Impact factor: 11.025

6.  High prevalence of genetic variants previously associated with Brugada syndrome in new exome data.

Authors:  B Risgaard; R Jabbari; L Refsgaard; A G Holst; S Haunsø; A Sadjadieh; B G Winkel; M S Olesen; J Tfelt-Hansen
Journal:  Clin Genet       Date:  2013-03-11       Impact factor: 4.438

Review 7.  Searching for genetic determinants in the new millennium.

Authors:  N J Risch
Journal:  Nature       Date:  2000-06-15       Impact factor: 49.962

Review 8.  Molecular genetic insights into cardiovascular disease.

Authors:  M T Keating; M C Sanguinetti
Journal:  Science       Date:  1996-05-03       Impact factor: 47.728

9.  Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk.

Authors:  Marylyn D Ritchie; Joshua C Denny; Rebecca L Zuvich; Dana C Crawford; Jonathan S Schildcrout; Lisa Bastarache; Andrea H Ramirez; Jonathan D Mosley; Jill M Pulley; Melissa A Basford; Yuki Bradford; Luke V Rasmussen; Jyotishman Pathak; Christopher G Chute; Iftikhar J Kullo; Catherine A McCarty; Rex L Chisholm; Abel N Kho; Christopher S Carlson; Eric B Larson; Gail P Jarvik; Nona Sotoodehnia; Teri A Manolio; Rongling Li; Daniel R Masys; Jonathan L Haines; Dan M Roden
Journal:  Circulation       Date:  2013-03-05       Impact factor: 29.690

10.  Human disease classification in the postgenomic era: a complex systems approach to human pathobiology.

Authors:  Joseph Loscalzo; Isaac Kohane; Albert-Laszlo Barabasi
Journal:  Mol Syst Biol       Date:  2007-07-10       Impact factor: 11.429
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  13 in total

Review 1.  Emerging Role of Precision Medicine in Cardiovascular Disease.

Authors:  Jane A Leopold; Joseph Loscalzo
Journal:  Circ Res       Date:  2018-04-27       Impact factor: 17.367

Review 2.  Towards Precision in HF Pharmacotherapy.

Authors:  Nicholas B Norgard; Carolyn Hempel
Journal:  Curr Heart Fail Rep       Date:  2017-02

Review 3.  Closing the 'phenotype gap' in precision medicine: improving what we measure to understand complex disease mechanisms.

Authors:  Calum A MacRae
Journal:  Mamm Genome       Date:  2019-08-19       Impact factor: 2.957

Review 4.  Molecular mechanisms in the pathogenesis of arrhythmogenic cardiomyopathy.

Authors:  Jeffrey E Saffitz
Journal:  Cardiovasc Pathol       Date:  2017-02-27       Impact factor: 2.185

5.  Delirium Severity Trajectories and Outcomes in ICU Patients. Defining a Dynamic Symptom Phenotype.

Authors:  Heidi Lindroth; Babar A Khan; Janet S Carpenter; Sujuan Gao; Anthony J Perkins; Sikandar H Khan; Sophia Wang; Richard N Jones; Malaz A Boustani
Journal:  Ann Am Thorac Soc       Date:  2020-09

6.  Perception of personalized medicine, pharmacogenomics, and genetic testing among undergraduates in Hong Kong.

Authors:  Nicholas Yan Chai Cheung; Jasmine Lee Fong Fung; Yvette Nga Chung Ng; Wilfred Hing Sang Wong; Claudia Ching Yan Chung; Christopher Chun Yu Mak; Brian Hon Yin Chung
Journal:  Hum Genomics       Date:  2021-08-18       Impact factor: 4.639

Review 7.  Modelling inherited cardiac disease using human induced pluripotent stem cell-derived cardiomyocytes: progress, pitfalls, and potential.

Authors:  Alain van Mil; Geerthe Margriet Balk; Klaus Neef; Jan Willem Buikema; Folkert W Asselbergs; Sean M Wu; Pieter A Doevendans; Joost P G Sluijter
Journal:  Cardiovasc Res       Date:  2018-12-01       Impact factor: 10.787

8.  A hypertension patient-derived iPSC model demonstrates a role for G protein-coupled estrogen receptor in hypertension risk and development.

Authors:  Natalie C Fredette; Eliyah Malik; Marah L Mukhtar; Eric R Prossnitz; Naohiro Terada
Journal:  Am J Physiol Cell Physiol       Date:  2020-08-12       Impact factor: 4.249

9.  Editorial: Current Challenges in Cardiovascular Molecular Diagnostics.

Authors:  Valeria Novelli; Matteo Vatta
Journal:  Front Cardiovasc Med       Date:  2017-09-01

10.  Circulating non-coding RNAs in biomarker-guided cardiovascular therapy: a novel tool for personalized medicine?

Authors:  David de Gonzalo-Calvo; Angela Vea; Christian Bär; Jan Fiedler; Liam S Couch; Carlos Brotons; Vicenta Llorente-Cortes; Thomas Thum
Journal:  Eur Heart J       Date:  2019-05-21       Impact factor: 29.983
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