Literature DB >> 27324081

Antibiotic stewardship in a tertiary care hospital of a developing country: establishment of a system and its application in a unit-GASP Initiative.

N Shafiq1, M Praveen Kumar2, V Gautam3, H Negi2, R Roat4, S Malhotra2, P Ray3, R Agarwal5, A Bhalla6, N Sharma6, R Singh4, G D Sharma7, L Bahadur7, N Yadanapudi8, R Gupta4, G Singh4.   

Abstract

PURPOSE: Despite the proven benefits of antimicrobial stewardship, models for executing the same in the developing countries are sparse. The present study highlights the approaches undertaken by our group in initiating one such program in a public sector tertiary level health care setting of a developing country.
METHODS: The study focussed on development of a system after evaluation of existing issues and case study of implementation of the program in a unit within the hospital. The system building exercise included (1) development of generic data capture form for prospective audit and feedback; (2) development of an electronic system for data capture; (3) identification of key intervention points for strategy decision for stewardship in a particular unit; (4) application of the stewardship method and (5) evaluation of outcomes.
RESULTS: A digital system for prospective audit was constructed after a background study. In the study unit, there was a significant decline in double anaerobic coverage. There was a significant decline in the average number of antimicrobials used per patients and a decrease in Defined Daily Dose of designated antimicrobials was noted. Additionally, there was an increase in the use of optimized doses.
CONCLUSION: A system for undertaking antimicrobial stewardship with a mechanism for prospective audit was put in place. The system may be adopted by other public sector hospitals of the developing country.

Entities:  

Keywords:  Antibiotic stewardship; Defined daily dose; Developing country; Electronic record; System; Tertiary care

Mesh:

Substances:

Year:  2016        PMID: 27324081     DOI: 10.1007/s15010-016-0913-z

Source DB:  PubMed          Journal:  Infection        ISSN: 0300-8126            Impact factor:   3.553


  30 in total

1.  Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship.

Authors:  Timothy H Dellit; Robert C Owens; John E McGowan; Dale N Gerding; Robert A Weinstein; John P Burke; W Charles Huskins; David L Paterson; Neil O Fishman; Christopher F Carpenter; P J Brennan; Marianne Billeter; Thomas M Hooton
Journal:  Clin Infect Dis       Date:  2006-12-13       Impact factor: 9.079

2.  Antimicrobial stewardship in institutions and office practices.

Authors:  Raju C Shah; Pratima Shah
Journal:  Indian J Pediatr       Date:  2008-08       Impact factor: 1.967

3.  A drug utilization study to provide background data for bringing amendments in the drug dispensing policy of a pediatric referral center.

Authors:  Inderjeet Singh; Rajan Mittal; Nusrat Shafiq; Bhavneet Bharati; Ramesh Kumar Nigah; P Pandhi; Ranjeet Roy Chaudhary; Samir Malhotra
Journal:  Pharmacoepidemiol Drug Saf       Date:  2010-04       Impact factor: 2.890

Review 4.  Antimicrobial use metrics and benchmarking to improve stewardship outcomes: methodology, opportunities, and challenges.

Authors:  Omar M Ibrahim; Ron E Polk
Journal:  Infect Dis Clin North Am       Date:  2014-06       Impact factor: 5.982

5.  Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America.

Authors:  Tamar F Barlam; Sara E Cosgrove; Lilian M Abbo; Conan MacDougall; Audrey N Schuetz; Edward J Septimus; Arjun Srinivasan; Timothy H Dellit; Yngve T Falck-Ytter; Neil O Fishman; Cindy W Hamilton; Timothy C Jenkins; Pamela A Lipsett; Preeti N Malani; Larissa S May; Gregory J Moran; Melinda M Neuhauser; Jason G Newland; Christopher A Ohl; Matthew H Samore; Susan K Seo; Kavita K Trivedi
Journal:  Clin Infect Dis       Date:  2016-04-13       Impact factor: 9.079

Review 6.  Antibiotic prophylaxis in severe acute pancreatitis.

Authors:  H G Beger; B Rau; R Isenmann; M Schwarz; F Gansauge; B Poch
Journal:  Pancreatology       Date:  2005-03-15       Impact factor: 3.996

7.  Impact of a clinical decision support system on pharmacy clinical interventions, documentation efforts, and costs.

Authors:  Stacy Calloway; Hameed A Akilo; Kyle Bierman
Journal:  Hosp Pharm       Date:  2013-10

8.  Emergence of Burkholderia pseudomallei and pandrug-resistant non-fermenters from southern Karnataka, India.

Authors:  Chiranjay Mukhopadhyay; Kiran Chawla; Sushma Krishna; N Nagalakshmi; Sugandhi P Rao; Indira Bairy
Journal:  Trans R Soc Trop Med Hyg       Date:  2008-12       Impact factor: 2.184

9.  Antibiotic resistance in pathogens causing community-acquired urinary tract infections in India: a multicenter study.

Authors:  Atul Kothari; Vishal Sagar
Journal:  J Infect Dev Ctries       Date:  2008-10-01       Impact factor: 0.968

10.  Drug utilization study in medical emergency unit of a tertiary care hospital in north India.

Authors:  Sharonjeet Kaur; Sujit Rajagopalan; Navjot Kaur; Nusrat Shafiq; Ashish Bhalla; Promila Pandhi; Samir Malhotra
Journal:  Emerg Med Int       Date:  2014-05-05       Impact factor: 1.112

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1.  Environmental pollution with antimicrobial agents from bulk drug manufacturing industries in Hyderabad, South India, is associated with dissemination of extended-spectrum beta-lactamase and carbapenemase-producing pathogens.

Authors:  Christoph Lübbert; Christian Baars; Anil Dayakar; Norman Lippmann; Arne C Rodloff; Martina Kinzig; Fritz Sörgel
Journal:  Infection       Date:  2017-04-26       Impact factor: 3.553

2.  Evaluating antibiotic stewardship in a tertiary care hospital in Kerala, India: a qualitative interview study.

Authors:  Kelsey Baubie; Catherine Shaughnessy; Lia Kostiuk; Mariam Varsha Joseph; Nasia Safdar; Sanjeev K Singh; Dawd Siraj; Ajay Sethi; Julie Keating
Journal:  BMJ Open       Date:  2019-05-14       Impact factor: 2.692

3.  Antimicrobial susceptibility patterns of organisms causing secondary abdominal infections in patients with perforated abdominal viscus.

Authors:  Praveen Kumar-M; Nusrat Shafiq; Pradeep Kumar; Ashish Gupta; Samir Malhotra; Naveen M; Vikas Gautam; Pallab Ray; Rajesh Gupta; Vikas Gupta; Thakur Deen Yadav; G R Verma; Rajinder Singh; Gurpreet Singh
Journal:  Ther Adv Infect Dis       Date:  2019-07-31

Review 4.  A proposal for a comprehensive approach to infections across the surgical pathway.

Authors:  Massimo Sartelli; Leonardo Pagani; Stefania Iannazzo; Maria Luisa Moro; Pierluigi Viale; Angelo Pan; Luca Ansaloni; Federico Coccolini; Marcello Mario D'Errico; Iris Agreiter; Giorgio Amadio Nespola; Francesco Barchiesi; Valeria Benigni; Raffaella Binazzi; Stefano Cappanera; Alessandro Chiodera; Valentina Cola; Daniela Corsi; Francesco Cortese; Massimo Crapis; Francesco Cristini; Alessandro D'Arpino; Belinda De Simone; Stefano Di Bella; Francesco Di Marzo; Abele Donati; Daniele Elisei; Massimo Fantoni; Anna Ferrari; Domitilla Foghetti; Daniela Francisci; Gianni Gattuso; Andrea Giacometti; Guido Cesare Gesuelli; Cristina Marmorale; Enrica Martini; Marcello Meledandri; Rita Murri; Daniela Padrini; Dalia Palmieri; Paola Pauri; Carla Rebagliati; Enrico Ricchizzi; Vittorio Sambri; Anna Maria Schimizzi; Walter Siquini; Loredana Scoccia; Giancarlo Scoppettuolo; Gabriele Sganga; Nadia Storti; Marcello Tavio; Giulio Toccafondi; Fabio Tumietto; Bruno Viaggi; Marco Vivarelli; Cristian Tranà; Melina Raso; Francesco Maria Labricciosa; Sameer Dhingra; Fausto Catena
Journal:  World J Emerg Surg       Date:  2020-02-18       Impact factor: 5.469

5.  Are Antibiotics Prescribed to Inpatients According to Recommended Standard Guidelines in South Sudan? A Retrospective Cross-Sectional Study in Juba Teaching Hospital.

Authors:  Michael E Otim; Desmond Kabuya Demaya; Amina Al Marzouqi; Jean Mukasa
Journal:  J Multidiscip Healthc       Date:  2021-10-13

6.  A study of antibiotic prescription pattern in patients referred to tertiary care center in Northern India.

Authors:  Amritpal Kaur; Rajan Bhagat; Navjot Kaur; Nusrat Shafiq; Vikas Gautam; Samir Malhotra; Vikas Suri; Ashish Bhalla
Journal:  Ther Adv Infect Dis       Date:  2018-05-10

Review 7.  Antimicrobial Stewardship Programs in Resource Constrained Environments: Understanding and Addressing the Need of the Systems.

Authors:  Ashish Kumar Kakkar; Nusrat Shafiq; Gurpreet Singh; Pallab Ray; Vikas Gautam; Ritesh Agarwal; Jayashree Muralidharan; Pankaj Arora
Journal:  Front Public Health       Date:  2020-04-28

8.  Antibiotic stewardship initiative in a Medicine unit of a tertiary care teaching hospital in India: A pilot study.

Authors:  Anitha Swamy; Rita Sood; Arti Kapil; Naval K Vikram; Piyush Ranjan; Ranveer Singh Jadon; Manish Soneja; V Sreenivas
Journal:  Indian J Med Res       Date:  2019-08       Impact factor: 2.375

  8 in total

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