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Literature DB >> 27322088

Invasive pneumococcal disease leads to activation and hyperreactivity of platelets.

Rahajeng N Tunjungputri¹, Marien I de Jonge², Astrid de Greeff³, Saskia van Selm², Herma Buys³, Jose F Harders-Westerveen³, Norbert Stockhofe-Zurwieden³, Rolf T Urbanus⁴, Phillip G de Groot⁵, Hilde E Smith³, Andre J van der Ven⁶, Quirijn de Mast⁶.

Abstract

Using a novel porcine model of intravenous Streptococcus pneumoniae infection, we showed that invasive pneumococcal infections induce marked platelet activation and hyperreactivity. This may contribute to the vascular complications seen in pneumococcal infection.

Entities: Disease

Keywords: Infection; Myocardial infarction; Platelet activation; Platelets; Pneumonia; Streptococcus pneumoniae

Mesh：

Year: 2016 PMID： 27322088 DOI： 10.1016/j.thromres.2016.06.016

Source DB: PubMed Journal: Thromb Res ISSN： 0049-3848 Impact factor: 3.944

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Cited

6 in total

Review 1. Contribution of Human Thrombospondin-1 to the Pathogenesis of Gram-Positive Bacteria.

Authors: Ulrike Binsker; Thomas P Kohler; Sven Hammerschmidt
Journal: J Innate Immun Date: 2019-02-27 Impact factor: 7.349

2. Platelet dysfunction contributes to bleeding complications in patients with probable leptospirosis.

Authors: Rahajeng N Tunjungputri; Muhammad Hussein Gasem; Willemijn van der Does; Pandu H Sasongko; Bambang Isbandrio; Rolf T Urbanus; Philip G de Groot; Andre van der Ven; Quirijn de Mast
Journal: PLoS Negl Trop Dis Date: 2017-09-21

3. Short- and long-term outcomes after incident pneumonia in adults with chronic kidney disease: a time-dependent analysis from the Stockholm CREAtinine Measurement project.

Authors: Guobin Su; Marco Trevisan; Junichi Ishigami; Kunihiro Matsushita; Cecilia Stålsby Lundborg; Juan Jesus Carrero
Journal: Nephrol Dial Transplant Date: 2020-11-01 Impact factor: 5.992

Invasive pneumococcal disease leads to activation and hyperreactivity of platelets.

Review 1. Contribution of Human Thrombospondin-1 to the Pathogenesis of Gram-Positive Bacteria.

2. Platelet dysfunction contributes to bleeding complications in patients with probable leptospirosis.

3. Short- and long-term outcomes after incident pneumonia in adults with chronic kidney disease: a time-dependent analysis from the Stockholm CREAtinine Measurement project.

Review 4. Platelets, Bacterial Adhesins and the Pneumococcus.

5. Infection in Living Donor Liver Transplantation Leads to Increased Risk of Adverse Renal Outcomes.

Review 6. Multifaceted Role of Pneumolysin in the Pathogenesis of Myocardial Injury in Community-Acquired Pneumonia.