Literature DB >> 27321479

Circulating endothelium-enriched microRNA-126 as a potential biomarker for coronary artery disease in type 2 diabetes mellitus patients.

Ghada Al-Kafaji1, Ghazi Al-Mahroos2, Haifa Abdulla Al-Muhtaresh1, Mohamed Abdalla Sabry1, Rima Abdul Razzak1, Abdel Halim Salem1.   

Abstract

Circulating microRNAs (miRNAs) have been shown as promising biomarkers for various diseases. We investigated the predictive potential of circulating endothelium-enriched miR-126 in type 2 diabetes patients (T2D) without chronic complications and T2D patients with coronary artery diseases (CAD). The expression levels of circulating miR-126, determined by quantitative real time PCR, were decrease in peripheral blood of T2D patients and T2D with CAD compared with healthy controls. MiR-126 strongly associated with T2D and CAD, negatively correlated with LDL in CAD patients and differentiated between T2D patients, T2D patients with CAD and healthy subjects. Circulating miR-126 may serve as a biomarker for predicting patients with T2D and diabetic CAD.

Entities:  

Keywords:  Biomarker; circulating miR-126; coronary artery disease; microRNAs; type 2 diabetes

Mesh：

Substances：

Year:  2016        PMID： 27321479     DOI： 10.1080/1354750X.2016.1204004

Source DB:  PubMed          Journal:  Biomarkers        ISSN： 1354-750X            Impact factor:   2.658


  23 in total

Review 1.  Circulating microRNAs and diabetes mellitus: a novel tool for disease prediction, diagnosis, and staging?

Authors:  G Sebastiani; L Nigi; G E Grieco; F Mancarella; G Ventriglia; F Dotta
Journal:  J Endocrinol Invest       Date:  2017-02-17       Impact factor: 4.256

2.  Blood-based microRNAs as diagnostic biomarkers to discriminate localized prostate cancer from benign prostatic hyperplasia and allow cancer-risk stratification.

Authors:  Ghada Al-Kafaji; Harun Muayad Said; Mahmood Abduljalil Alam; Ziad Tarraq Al Naieb
Journal:  Oncol Lett       Date:  2018-05-22       Impact factor: 2.967

3.  Upregulation of Circulating Cardiomyocyte-Enriched miR-1 and miR-133 Associate with the Risk of Coronary Artery Disease in Type 2 Diabetes Patients and Serve as Potential Biomarkers.

Authors:  Haifa Abdulla Al-Muhtaresh; Abdel Halim Salem; Ghada Al-Kafaji
Journal:  J Cardiovasc Transl Res       Date:  2019-01-04       Impact factor: 4.132

Review 4.  Molecular Approaches in HFpEF: MicroRNAs and iPSC-Derived Cardiomyocytes.

Authors:  Alison J Kriegel; Melanie Gartz; Muhammad Z Afzal; Willem J de Lange; J Carter Ralphe; Jennifer L Strande
Journal:  J Cardiovasc Transl Res       Date:  2016-12-28       Impact factor: 4.132

5.  Salivary microRNA-126 and 135a: a potentially non-invasive diagnostic biomarkers of type- 2 diabetes.

Authors:  Yousef Khazaei Monfared; Mohammad-Reza Mirzaii-Dizgah; Elham Khodabandehloo; Mohamad Reza Sarookhani; Sima Hashemipour; Iraj Mirzaii-Dizgah
Journal:  J Diabetes Metab Disord       Date:  2021-10-28

6.  Relationship of miRNA‑126 and miRNA‑122 expression with type 2 diabetes mellitus and related glucose metabolism parameters: A systematic review and meta‑analysis.

Authors:  Yaling He; Yuqian Li; Zhihan Zhai; Pengling Liu; Luting Nie; Yiquan Zheng; Jian Hou; Wenqian Huo; Zhenxing Mao; Zhenzhong Zhang; Chongjian Wang; Xiaotian Liu
Journal:  Exp Ther Med       Date:  2022-09-05       Impact factor: 2.751

7.  Micro-ribonucleic acid modulation with oxidative stress and inflammation in patients with type 2 diabetes mellitus - a review article.

Authors:  Aleksandra Klisic; Irena Radoman Vujacic; Jelena Munjas; Ana Ninic; Jelena Kotur-Stevuljevic
Journal:  Arch Med Sci       Date:  2022-04-10       Impact factor: 3.707

Review 8.  Regulatory Roles of MicroRNAs in Diabetes.

Authors:  Juan Feng; Wanli Xing; Lan Xie
Journal:  Int J Mol Sci       Date:  2016-10-17       Impact factor: 5.923

Review 9.  microRNA in Cardiovascular Aging and Age-Related Cardiovascular Diseases.

Authors:  Claudio de Lucia; Klara Komici; Giulia Borghetti; Grazia Daniela Femminella; Leonardo Bencivenga; Alessandro Cannavo; Graziamaria Corbi; Nicola Ferrara; Steven R Houser; Walter J Koch; Giuseppe Rengo
Journal:  Front Med (Lausanne)       Date:  2017-06-12

Review 10.  Epigenetics, microRNA and Metabolic Syndrome: A Comprehensive Review.

Authors:  Farha Ramzan; Mark H Vickers; Richard F Mithen
Journal:  Int J Mol Sci       Date:  2021-05-10       Impact factor: 5.923
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.