Literature DB >> 273209

Aplasia and leukaemia following chloroquine therapy.

N Nagaratnam, A D Chetiyawardana, S Rajiyah.   

Abstract

Three patients with aplastic anaemia following chloroquine therapy are described. In two, chloroquine had been administered in large doses over a long period. One of them subsequently developed acute myeloblastic leukaemia. The third received only a small dose and pancytopenia with aplasia followed three weeks after ingestion of the drug. The mechanism(s) of chloroquine-induced marrow injury is not known. A parallel to chloramphenicol-induced blood dyscrasias is drawn, but remains unproved.

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Year:  1978        PMID: 273209      PMCID: PMC2425073          DOI: 10.1136/pgmj.54.628.108

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  6 in total

1.  ACUTE LEUKAEMIA ASSOCIATED WITH PHENYLBUTAZONE TREATMENT: A REVIEW OF THE LITERATURE AND REPORT OF A FURTHER CASE.

Authors:  L DOUGAN; H J WOODLIFF
Journal:  Med J Aust       Date:  1965-02-13       Impact factor: 7.738

Review 2.  CHLORAMPHENICOL TOXICITY: CLINICAL FEATURES AND PATHOGENESIS.

Authors:  A A YUNIS; G R BLOOMBERG
Journal:  Prog Hematol       Date:  1964

3.  Acute myeloblastic leukaemia following chloramphenicol treatment.

Authors:  P S MUKHERJI
Journal:  Br Med J       Date:  1957-06-01

Review 4.  Malaria--recent progress and problems.

Authors:  F A Neva
Journal:  N Engl J Med       Date:  1967-12-07       Impact factor: 91.245

5.  Preleukemia. The hematologic syndrome preceding acute leukemia.

Authors:  M I Saarni; J W Linman
Journal:  Am J Med       Date:  1973-07       Impact factor: 4.965

6.  Agranulocytosis and hydroxychloroquine.

Authors:  R P Propp; J S Stillman
Journal:  N Engl J Med       Date:  1967-08-31       Impact factor: 91.245

  6 in total
  7 in total

Review 1.  Antimalarial drug toxicity: a review.

Authors:  W Robert J Taylor; Nicholas J White
Journal:  Drug Saf       Date:  2004       Impact factor: 5.606

Review 2.  A risk-benefit assessment of slow-acting antirheumatic drugs in rheumatoid arthritis.

Authors:  A A Kalla; A F Tooke; E Bhettay; O L Meyers
Journal:  Drug Saf       Date:  1994-07       Impact factor: 5.606

3.  Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents.

Authors:  Ciska Verbaanderd; Hannelore Maes; Marco B Schaaf; Vikas P Sukhatme; Pan Pantziarka; Vidula Sukhatme; Patrizia Agostinis; Gauthier Bouche
Journal:  Ecancermedicalscience       Date:  2017-11-23

Review 4.  Repurposing Chloroquine Against Multiple Diseases With Special Attention to SARS-CoV-2 and Associated Toxicity.

Authors:  Siya Kamat; Madhuree Kumari
Journal:  Front Pharmacol       Date:  2021-04-12       Impact factor: 5.810

5.  Spirulina platensis Alleviated the Hemotoxicity, Oxidative Damage and Histopathological Alterations of Hydroxychloroquine in Catfish (Clarias gariepinus).

Authors:  Alaa El-Din H Sayed; Mohamed Hamed; Hamdy A M Soliman
Journal:  Front Physiol       Date:  2021-07-06       Impact factor: 4.566

Review 6.  Chemically induced leukemia in humans.

Authors:  R H Adamson; S M Seiber
Journal:  Environ Health Perspect       Date:  1981-06       Impact factor: 9.031

Review 7.  Bisphosphonates for delivering drugs to bone.

Authors:  Shuting Sun; Jianguo Tao; Parish P Sedghizadeh; Philip Cherian; Adam F Junka; Esmat Sodagar; Lianping Xing; Robert K Boeckman; Venkatesan Srinivasan; Zhenqiang Yao; Brendan F Boyce; Brea Lipe; Jeffrey D Neighbors; R Graham G Russell; Charles E McKenna; Frank H Ebetino
Journal:  Br J Pharmacol       Date:  2021-04-10       Impact factor: 8.739

  7 in total

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