Literature DB >> 27319127

Two New Triterpenoid Saponins from the Structural Modification of Pseudoginsenoside-F11 and their Cytotoxic Activities.

Manman Li, Zhicai Wang, Pengfei Zhang, Yan Xua, Hongda Ding, Dayuan Sui, Huali Xu, Yanping Chen.   

Abstract

Two ginsenoside derivatives (1, 2) along with 2 known ginsenosides (3, 4) were isolated from the acid hydrolysis products of pseudoginsenoside-F11. Their structures were elucidated on the basis of spectroscopic analyses, including ID, 2D NMR and HR-ESI-MS. Among them, (12R, 20S, 24S)-20, 24; 12, 24-diepoxy-dammarane-3β, 6α-diol (1) and (20R, 24R)-dammar-20, 24-epoxy-3β, 6α, 12β, 25-tetraol (2) were identified as new triterpenoid saponins. They were subjected to assay for cytotoxic activities against six human tumor cells lines.

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Year:  2016        PMID: 27319127

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN: 1555-9475            Impact factor:   0.986


  1 in total

1.  Mass Spectrometry Based Profiling and Imaging of Various Ginsenosides from Panax ginseng Roots at Different Ages.

Authors:  Jae Won Lee; Seung-Heon Ji; Young-Seob Lee; Doo Jin Choi; Bo-Ram Choi; Geum-Soog Kim; Nam-In Baek; Dae Young Lee
Journal:  Int J Mol Sci       Date:  2017-05-24       Impact factor: 5.923

  1 in total

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