| Literature DB >> 27319009 |
L Bartalena1, L Chiovato2, P Vitti3.
Abstract
Graves' disease is the most common cause of hyperthyroidism in iodine-replete areas. Although progress has been made in our understanding of the pathogenesis of the disease, no treatment targeting pathogenic mechanisms of the disease is presently available. Therapies for Graves' hyperthyroidism are largely imperfect because they are bound to either a high rate of relapsing hyperthyroidism (antithyroid drugs) or lifelong hypothyroidism (radioiodine treatment or thyroidectomy). Aim of the present article is to offer a practical guidance to the reader by providing evidence-based answers to frequently asked questions in clinical practice.Entities:
Keywords: Agranulocytosis; Alemtuzumab; Childhood; Graves’ disease; Graves’ orbitopathy; Hyperthyroidism; Methimazole; Pregnancy; Propylthiouracil; Radioiodine; Thionamides; Thyroidectomy
Mesh:
Year: 2016 PMID: 27319009 DOI: 10.1007/s40618-016-0505-x
Source DB: PubMed Journal: J Endocrinol Invest ISSN: 0391-4097 Impact factor: 4.256