Literature DB >> 27318871

Stem cell based therapies for spinal cord injury.

Aikeremujiang Muheremu1, Jiang Peng2, Qiang Ao3.   

Abstract

Treatment of spinal cord injury has always been a challenge for clinical practitioners and scientists. The development in stem cell based therapies has brought new hopes to patients with spinal cord injuries. In the last a few decades, a variety of stem cells have been used to treat spinal cord injury in animal experiments and some clinical trials. However, there are many technical and ethical challenges to overcome before this novel therapeutic method can be widely applied in clinical practice. With further research in pluripotent stem cells and combined application of genetic and tissue engineering techniques, stem cell based therapies are bond to play increasingly important role in the management of spinal cord injuries.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Spinal cord injury; Stem cell; Transplantation

Mesh:

Year:  2016        PMID: 27318871     DOI: 10.1016/j.tice.2016.05.008

Source DB:  PubMed          Journal:  Tissue Cell        ISSN: 0040-8166            Impact factor:   2.466


  14 in total

1.  Protective effect of Oxymatrine against acute spinal cord injury in rats via modulating oxidative stress, inflammation and apoptosis.

Authors:  Binggang Guan; Rongchun Chen; Mingliang Zhong; Ning Liu; Qin Chen
Journal:  Metab Brain Dis       Date:  2019-12-15       Impact factor: 3.584

2.  Multichannel polymer scaffold seeded with activated Schwann cells and bone mesenchymal stem cells improves axonal regeneration and functional recovery after rat spinal cord injury.

Authors:  Er-Zhu Yang; Guo-Wang Zhang; Jian-Guang Xu; Shuai Chen; Hua Wang; Liang-Liang Cao; Bo Liang; Xiao-Feng Lian
Journal:  Acta Pharmacol Sin       Date:  2017-04-10       Impact factor: 6.150

Review 3.  Progress in Stem Cell Therapy for Spinal Cord Injury.

Authors:  Liansheng Gao; Yucong Peng; Weilin Xu; Pingyou He; Tao Li; Xiaoyang Lu; Gao Chen
Journal:  Stem Cells Int       Date:  2020-11-05       Impact factor: 5.443

Review 4.  Biomaterial Scaffolds in Regenerative Therapy of the Central Nervous System.

Authors:  Yanchao Wang; Hong Tan; Xuhui Hui
Journal:  Biomed Res Int       Date:  2018-04-01       Impact factor: 3.411

5.  A partition-type tubular scaffold loaded with PDGF-releasing microspheres for spinal cord repair facilitates the directional migration and growth of cells.

Authors:  Xue Chen; Mei-Ling Xu; Cheng-Niu Wang; Lu-Zhong Zhang; Ya-Hong Zhao; Chang-Lai Zhu; Ying Chen; Jian Wu; Yu-Min Yang; Xiao-Dong Wang
Journal:  Neural Regen Res       Date:  2018-07       Impact factor: 5.135

6.  The Prognostic Value of Serum Neuron Specific Enolase (NSE) and S100B Level in Patients of Acute Spinal Cord Injury.

Authors:  Wenjun Du; Huinan Li; Juan Sun; Yingpeng Xia; Rusen Zhu; Xueli Zhang; Rong Tian
Journal:  Med Sci Monit       Date:  2018-06-30

7.  Label-free multiphoton microscopy reveals relevant tissue changes induced by alginate hydrogel implantation in rat spinal cord injury.

Authors:  Roberta Galli; Kerim H Sitoci-Ficici; Ortrud Uckermann; Robert Later; Magda Marečková; Maria Koch; Elke Leipnitz; Gabriele Schackert; Edmund Koch; Michael Gelinsky; Gerald Steiner; Matthias Kirsch
Journal:  Sci Rep       Date:  2018-07-18       Impact factor: 4.379

8.  A scoping review of trials for cell-based therapies in human spinal cord injury.

Authors:  Alice G Willison; Sam Smith; Benjamin M Davies; Mark R N Kotter; Susan C Barnett
Journal:  Spinal Cord       Date:  2020-04-06       Impact factor: 2.772

9.  Collagen-Binding Hepatocyte Growth Factor (HGF) alone or with a Gelatin- furfurylamine Hydrogel Enhances Functional Recovery in Mice after Spinal Cord Injury.

Authors:  Kentaro Yamane; Tetsuro Mazaki; Yasuyuki Shiozaki; Aki Yoshida; Kensuke Shinohara; Mariko Nakamura; Yasuhiro Yoshida; Di Zhou; Takashi Kitajima; Masato Tanaka; Yoshihiro Ito; Toshifumi Ozaki; Akihiro Matsukawa
Journal:  Sci Rep       Date:  2018-01-17       Impact factor: 4.379

10.  Endothelial progenitor cell-conditioned medium promotes angiogenesis and is neuroprotective after spinal cord injury.

Authors:  Tao Wang; Xiao Fang; Zong-Sheng Yin
Journal:  Neural Regen Res       Date:  2018-05       Impact factor: 5.135

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