Qian Xiao1, Lisa B Signorello2, Louise A Brinton3, Sarah S Cohen4, William J Blot5, Charles E Matthews6. 1. Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA. Electronic address: qian.xiao@nih.gov. 2. Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Rockville, MD, USA. 3. Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA. 4. International Epidemiology Institute, Rockville, MD, USA. 5. International Epidemiology Institute, Rockville, MD, USA; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. 6. Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Abstract
BACKGROUND: Sleep has been suggested to influence breast cancer risk; however, the evidence is mixed. Black women have a higher prevalence of both short (<6 h) and long (≥9 h) sleep duration and are more likely to develop more aggressive, hormone receptor-negative breast cancer. No study has examined the relationship between sleep and breast cancer in blacks. We focused on race-specific associations among the blacks. METHODS: In the Southern Community Cohort Study (SCCS), a prospective study of which two-thirds of the population were black, we prospectively investigated self-reported sleep duration in relation to overall breast cancer risk by estrogen (ER) and progesterone receptor (PR) status in all women and in black women alone. RESULTS: Sleep duration was not associated with risk of total or hormone receptor-positive breast cancer. However, we found an inverse relationship between sleep duration and risk of ER- and PR- breast cancer among all women and in black women alone. Compared to the reference group (8 h), black women who reported shorter sleep duration had an increased risk of ER- PR- breast cancer (odds ratios; ORs (95% confidence intervals; CIs): 2.13 (1.15, 3.93), 1.66 (0.92, 3.02), and 2.22 (1.19, 4.12) for <6, 6, and 7 h, respectively, (p for trend, 0.04). CONCLUSIONS: Short sleep duration may be a risk factor for hormone receptor-negative breast cancer among black women. Published by Elsevier B.V.
BACKGROUND: Sleep has been suggested to influence breast cancer risk; however, the evidence is mixed. Black women have a higher prevalence of both short (<6 h) and long (≥9 h) sleep duration and are more likely to develop more aggressive, hormone receptor-negative breast cancer. No study has examined the relationship between sleep and breast cancer in blacks. We focused on race-specific associations among the blacks. METHODS: In the Southern Community Cohort Study (SCCS), a prospective study of which two-thirds of the population were black, we prospectively investigated self-reported sleep duration in relation to overall breast cancer risk by estrogen (ER) and progesterone receptor (PR) status in all women and in black women alone. RESULTS: Sleep duration was not associated with risk of total or hormone receptor-positive breast cancer. However, we found an inverse relationship between sleep duration and risk of ER- and PR- breast cancer among all women and in black women alone. Compared to the reference group (8 h), black women who reported shorter sleep duration had an increased risk of ER- PR- breast cancer (odds ratios; ORs (95% confidence intervals; CIs): 2.13 (1.15, 3.93), 1.66 (0.92, 3.02), and 2.22 (1.19, 4.12) for <6, 6, and 7 h, respectively, (p for trend, 0.04). CONCLUSIONS:Short sleep duration may be a risk factor for hormone receptor-negative breast cancer among black women. Published by Elsevier B.V.
Entities:
Keywords:
Black women; Breast cancer; Hormone receptor-negative breast cancer; Hormone receptor-positive breast cancer; Sleep
Authors: F Wang; K L Yeung; W C Chan; C C H Kwok; S L Leung; C Wu; E Y Y Chan; I T S Yu; X R Yang; L A Tse Journal: Ann Oncol Date: 2013-08-23 Impact factor: 32.976
Authors: Lisa B Signorello; Margaret K Hargreaves; Mark D Steinwandel; Wei Zheng; Qiuyin Cai; David G Schlundt; Maciej S Buchowski; Carolyne W Arnold; Joseph K McLaughlin; William J Blot Journal: J Natl Med Assoc Date: 2005-07 Impact factor: 1.798
Authors: Eva S Schernhammer; Franco Berrino; Vittorio Krogh; Giorgio Secreto; Andrea Micheli; Elisabetta Venturelli; Sara Grioni; Christopher T Sempos; Adalberto Cavalleri; Holger J Schünemann; Sabrina Strano; Paola Muti Journal: Cancer Epidemiol Biomarkers Prev Date: 2010-03-03 Impact factor: 4.254
Authors: Emily Vogtmann; Emily B Levitan; Lauren Hale; James M Shikany; Neomi A Shah; Yohannes Endeshaw; Cora E Lewis; Joann E Manson; Rowan T Chlebowski Journal: Sleep Date: 2013-10-01 Impact factor: 5.849
Authors: M Kakizaki; S Kuriyama; T Sone; K Ohmori-Matsuda; A Hozawa; N Nakaya; S Fukudo; I Tsuji Journal: Br J Cancer Date: 2008-09-23 Impact factor: 7.640
Authors: N F Watson; D Buchwald; J J Delrow; W A Altemeier; M V Vitiello; A I Pack; M Bamshad; C Noonan; S A Gharib Journal: Sleep Date: 2017-01-01 Impact factor: 5.849
Authors: Maryssa Shigesato; Yosuke Kawai; Cherie Guillermo; Fadi Youkhana; Yurii B Shvetsov; Veronica W Setiawan; Christopher A Haiman; Loïc Le Marchand; Gertraud Maskarinec Journal: Int J Cancer Date: 2019-04-10 Impact factor: 7.396
Authors: Alexandra J White; Clarice R Weinberg; Yong-Moon Park; Aimee A D'Aloisio; Emily Vogtmann; Hazel B Nichols; Dale P Sandler Journal: Int J Cancer Date: 2017-08-22 Impact factor: 7.396
Authors: Allison Soucise; Caila Vaughn; Cheryl L Thompson; Amy E Millen; Jo L Freudenheim; Jean Wactawski-Wende; Amanda I Phipps; Lauren Hale; Lihong Qi; Heather M Ochs-Balcom Journal: Breast Cancer Res Treat Date: 2017-04-17 Impact factor: 4.872
Authors: Arthur Sillah; Nathaniel F Watson; Ulrike Peters; Mary L Biggs; F Javier Nieto; Christopher I Li; David Gozal; Timothy Thornton; Sonnah Barrie; Amanda I Phipps Journal: Cancer Epidemiol Date: 2021-11-17 Impact factor: 2.984
Authors: Claudia Trudel-Fitzgerald; Eric S Zhou; Elizabeth M Poole; Xuehong Zhang; Karin B Michels; A Heather Eliassen; Wendy Y Chen; Michelle D Holmes; Shelley S Tworoger; Eva S Schernhammer Journal: Br J Cancer Date: 2017-03-30 Impact factor: 7.640
Authors: Guy Fagherazzi; Douae El Fatouhi; Alice Bellicha; Amin El Gareh; Aurélie Affret; Courtney Dow; Lidia Delrieu; Matthieu Vegreville; Alexis Normand; Jean-Michel Oppert; Gianluca Severi Journal: J Med Internet Res Date: 2017-10-23 Impact factor: 5.428