Literature DB >> 27317700

Factors associated with successful revascularization using the aspiration component of ADAPT in the treatment of acute ischemic stroke.

Justin R Mascitelli1, Christopher P Kellner1, Chesney S Oravec2, Reade A De Leacy1, Eric K Oermann1, Kurt Yaeger1, Srinivasan Paramasivam1, Johanna T Fifi1, J Mocco1.   

Abstract

INTRODUCTION: ADAPT (a direct aspiration first pass technique) has been shown to be fast, cost-effective, and associated with excellent angiographic and clinical outcomes in the treatment of acute ischemic stroke (AIS).
OBJECTIVE: To identify any and all preoperative factors that are associated with successful revascularization using aspiration alone.
METHODS: A retrospective review of 76 patients with AIS treated with thrombectomy was carried out. Cohort 1 included cases in which aspiration alone was successful (Thrombolysis in Cerebral Infarction 2b or 3). Cohort 2 included cases in which aspiration was unsuccessful or could not be performed despite an attempt.
RESULTS: There was no difference between cohorts in gender, race, medications, National Institute of Health Stroke Scale score, IV tissue plasminogen activator, site or side of the occlusion, dense vessel sign, aortic arch type, severe stenosis, clot length, operator years of experience, and guide/aspiration catheters used. Patients in cohort 1 were on average younger (66.5 vs 74.1 years, p=0.025). There was a trend for more patients in cohort 2 to have atrial fibrillation/arrhythmias (62.5% vs 45.5%, p=0.168) and have a cardiogenic stroke etiology (78.1% vs 56.8%, p=0.086). There was also a trend for more reverse curves (2.3 vs 1.7, p=0.107), larger vessel diameter (3.26 mm vs 2.88 mm, p=0.184), larger vessel-to-catheter ratio (2.09 vs 1.87, p=0.192), and worse clot burden score (5.38 vs 6.68, p=0.104) in cohort 2.
CONCLUSIONS: Aspiration success was associated with younger age. Our findings suggest that ADAPT can be used for the vast majority of patients but it may be beneficial to use a different method first in the elderly. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Entities:  

Keywords:  Stroke; Thrombectomy

Mesh:

Year:  2016        PMID: 27317700     DOI: 10.1136/neurintsurg-2016-012439

Source DB:  PubMed          Journal:  J Neurointerv Surg        ISSN: 1759-8478            Impact factor:   5.836


  4 in total

1.  Direct aspiration for thrombectomy in ischemic stroke: Impact of dwell time.

Authors:  Cyril Chivot; Julie Renier; Hervé Deramond; Roger Bouzerar; Thierry Yzet
Journal:  Interv Neuroradiol       Date:  2019-11-07       Impact factor: 1.610

2.  First-line contact aspiration vs stent-retriever thrombectomy in acute ischemic stroke patients with large-artery occlusion in the anterior circulation: Systematic review and meta-analysis.

Authors:  Marion Boulanger; Bertrand Lapergue; Francis Turjman; Emmanuel Touzé; René Anxionnat; Serge Bracard; Michel Piotin; Benjamin Gory
Journal:  Interv Neuroradiol       Date:  2019-02-04       Impact factor: 1.610

3.  Improving endovascular access to the target vessel for thrombus aspiration -Use of the wedge device to overcome anatomic hurdles.

Authors:  Roisin M O'Cearbhaill; J Alderson; S Power; D B Herlihy; P Brennan; A O'Hare; J Thornton
Journal:  Interv Neuroradiol       Date:  2021-06-14       Impact factor: 1.764

4.  Clot imaging characteristics predict first pass effect of aspiration-first approach to thrombectomy.

Authors:  Muhammad Waqas; Weizhe Li; Tatsat R Patel; Felix Chin; Vincent M Tutino; Rimal H Dossani; Zeguang Ren; Waldo R Guerrero; Cesario V Borlongan; Elliot Pressman; Kenneth Snyder; Jason M Davies; Elad I Ley; Ciprian N Ionita; Adnan H Siddiqui; Maxim Mokin
Journal:  Interv Neuroradiol       Date:  2021-05-18       Impact factor: 1.764

  4 in total

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