Literature DB >> 27317607

Innovative metabolic operations.

Ricardo Cohen1, Pedro Paulo Caravatto2, Tarissa Zanata Petry2.   

Abstract

Bariatric surgery was developed with the aim of weight reduction. Success was defined only by excess weight loss. Other indices of resolution of metabolic co-morbidities were reported but were mostly secondary. Several communications have reported that regardless of body mass index (BMI), complete or partial remission of type 2 diabetes (T2D) is possible with such traditional gastrointestinal operations as the Roux-en-Y gastric bypass, bileopancreatic diversion, and sleeve gastrectomy. These results mostly occur before weight loss, positioning metabolic surgery as a good tool for controlling the current T2D epidemic. Surgery aimed mainly at the diseases, such as diabetes, and not weight loss are referred to as metabolic surgery. Metabolic surgery can effectively treat T2D in individuals with any BMI, including that below 35 kg/m(2). Concurrently, some new procedures were developed to treat patients that in theory do not need massive weight loss, focusing on a pathophysiological approach to T2D. Those new techniques, mainly duodenal jejunal bypass, ileal transposition, single-anastomosis duodenal ileal or jejunal bypass with sleeve gastrectomy, and the endoscopic duodenal liner, are experimental procedures, most reporting good metabolic control initially without relation to weight variation.
Copyright © 2016 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Bariatric surgery; Duodenal jejunal bypass; Gastrointestinal surgery; Ileal transposition; Innovative metabolic procedures; Metabolic surgery; Obesity; Type 2 diabetes mellitus

Mesh:

Year:  2016        PMID: 27317607     DOI: 10.1016/j.soard.2016.02.034

Source DB:  PubMed          Journal:  Surg Obes Relat Dis        ISSN: 1550-7289            Impact factor:   4.734


  4 in total

Review 1.  The Emergence of "Simpler" Surgical Options to Treat Obesity and Metabolic Syndrome.

Authors:  Ricardo Cohen
Journal:  Curr Atheroscler Rep       Date:  2017-11-02       Impact factor: 5.113

2.  The characterization of metabolites alterations in white adipose tissue of diabetic GK Rats after ileal transposition surgery by an untargeted metabolomics approach.

Authors:  Xiaorui Lyu; Kemin Yan; Weijie Chen; Yujie Wang; Huijuan Zhu; Hui Pan; Guole Lin; Linjie Wang; Hongbo Yang; Fengying Gong
Journal:  Adipocyte       Date:  2021-12       Impact factor: 4.534

3.  Ileal Transposition Surgery Decreases Fat Mass and Improves Glucose Metabolism in Diabetic GK Rats: Possible Involvement of FGF21.

Authors:  Kemin Yan; Weijie Chen; Huijuan Zhu; Guole Lin; Hui Pan; Naishi Li; Linjie Wang; Hongbo Yang; Meijuan Liu; Fengying Gong
Journal:  Front Physiol       Date:  2018-03-09       Impact factor: 4.566

4.  Ileal transposition helps to regulate plasma hepatokine levels in obese Zucker (Crl:ZUC(ORL)-Leprfa) rats.

Authors:  Dominika Stygar; Tomasz Sawczyn; Agnieszka Dulska; Elżbieta Chełmecka; Łukasz Mielańczyk; Natalia Matysiak; Michał Kukla; Maciej Idzik; Jan Augustyniak; Andrzej Gabriel; Konrad Karcz; Jerzy Jochem
Journal:  Sci Rep       Date:  2021-04-08       Impact factor: 4.379

  4 in total

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