K Meenakshi1, M Rajendran2, S Srikumar2, Sundar Chidambaram2. 1. Department of Cardiology, Madras Medical College, Chennai, India. Electronic address: drmeenaram@gmail.com. 2. Department of Cardiology, Madras Medical College, Chennai, India.
Abstract
OBJECTIVE: Epicardial fat is considered as indicator of cardiovascular risk. Several studies have tested the association between epicardial fat thickness (EFT) and coronary artery disease. The aim of our study is to test the hypothesis that echocardiographic EFT is a marker of coronary artery disease. METHODS: One hundred and ten patients (70 males and 40 females with mean age of 51.5±10.6 and 52.6±9.6, respectively) admitted for coronary angiogram underwent assessment of epicardial fat thickness by echocardiography. Routine clinical examination, evaluation of risk factor profile, and anthropometric variables were also done. Epicardial fat thickness was measured on the free wall of right ventricle in parasternal long- and short-axis views at end-systole for 3 cardiac cycles. RESULTS: Mean epicardial fat thickness in angiographically normal patients and acute coronary syndromes were 4.4±1.2 and 6.9±1.9, respectively. Epicardial fat thickness in males and females were not statistically different. Burden of coronary arterial lesions denoted by Gensini score shows linear association with epicardial fat thickness and the severity of the coronary disease. CONCLUSION: Epicardial fat is independently and linearly associated with CAD and its severity.
OBJECTIVE: Epicardial fat is considered as indicator of cardiovascular risk. Several studies have tested the association between epicardial fat thickness (EFT) and coronary artery disease. The aim of our study is to test the hypothesis that echocardiographic EFT is a marker of coronary artery disease. METHODS: One hundred and ten patients (70 males and 40 females with mean age of 51.5±10.6 and 52.6±9.6, respectively) admitted for coronary angiogram underwent assessment of epicardial fat thickness by echocardiography. Routine clinical examination, evaluation of risk factor profile, and anthropometric variables were also done. Epicardial fat thickness was measured on the free wall of right ventricle in parasternal long- and short-axis views at end-systole for 3 cardiac cycles. RESULTS: Mean epicardial fat thickness in angiographically normal patients and acute coronary syndromes were 4.4±1.2 and 6.9±1.9, respectively. Epicardial fat thickness in males and females were not statistically different. Burden of coronary arterial lesions denoted by Gensini score shows linear association with epicardial fat thickness and the severity of the coronary disease. CONCLUSION: Epicardial fat is independently and linearly associated with CAD and its severity.
Authors: Jin-Won Jeong; Myung Ho Jeong; Kyeong Ho Yun; Seok Kyu Oh; Eun Mi Park; Yun Kyung Kim; Sang Jae Rhee; Eun Mi Lee; Je Lee; Nam Jin Yoo; Nam-Ho Kim; Jong Chun Park Journal: Circ J Date: 2007-04 Impact factor: 2.993
Authors: Guido A Rosito; Joseph M Massaro; Udo Hoffmann; Frederick L Ruberg; Amir A Mahabadi; Ramachandran S Vasan; Christopher J O'Donnell; Caroline S Fox Journal: Circulation Date: 2008-01-22 Impact factor: 29.690
Authors: M Demirpence; A Guler; H Yilmaz; A Sayin; Y Pekcevik; H Turkon; A Colak; E M Ari; B Aslanipour; G U Kocabas; M Calan Journal: J Endocrinol Invest Date: 2018-05-26 Impact factor: 4.256
Authors: Eric T Rasmussen; Eric C Shiao; Lee Zourelias; Michael S Halbreiner; Michael J Passineau; Srinivas Murali; Cameron N Riviere Journal: Int J Med Robot Date: 2021-06-14 Impact factor: 2.483