Literature DB >> 27314103

The Hippo-YAP/TAZ pathway mediates geranylgeranylation signaling in breast cancer progression.

Qiong Lin1, Wannian Yang2.   

Abstract

Protein geranylgeranylation (GGylation) regulates the function of various signal transducers including small GTPases and Ggamma subunits. The role of GGylation in breast cancer progression is poorly understood. Recent studies suggest that GGylation promotes the proliferation and migration of breast carcinoma cells through the Hippo-YAP/TAZ pathway.

Entities:  

Keywords:  Breast cancer; TAZ; YAP; geranylgeranylation; the Hippo pathway

Year:  2016        PMID： 27314103      PMCID： PMC4909444          DOI： 10.4161/23723548.2014.969638

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

1.  G protein betagamma subunits induce stress fiber formation and focal adhesion assembly in a Rho-dependent manner in HeLa cells.

Authors:  H Ueda; H Itoh; J Yamauchi; R Morishita; Y Kaziro; K Kato; T Asano
Journal:  J Biol Chem       Date:  2000-01-21       Impact factor: 5.157

2.  Proteomic analysis of bovine brain G protein gamma subunit processing heterogeneity.

Authors:  Lana A Cook; Kevin L Schey; Michael D Wilcox; Jane Dingus; Rebecca Ettling; Troy Nelson; Daniel R Knapp; John D Hildebrandt
Journal:  Mol Cell Proteomics       Date:  2005-12-06       Impact factor: 5.911

3.  Metabolic control of YAP and TAZ by the mevalonate pathway.

Authors:  Giovanni Sorrentino; Naomi Ruggeri; Valeria Specchia; Michelangelo Cordenonsi; Miguel Mano; Sirio Dupont; Andrea Manfrin; Eleonora Ingallina; Roberta Sommaggio; Silvano Piazza; Antonio Rosato; Stefano Piccolo; Giannino Del Sal
Journal:  Nat Cell Biol       Date:  2014-03-23       Impact factor: 28.824

4.  Geranylgeranylation signals to the Hippo pathway for breast cancer cell proliferation and migration.

Authors:  W Mi; Q Lin; C Childress; M Sudol; J Robishaw; C H Berlot; M Shabahang; W Yang
Journal:  Oncogene       Date:  2014-08-11       Impact factor: 9.867

5.  Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors.

Authors:  T Kusama; M Mukai; T Iwasaki; M Tatsuta; Y Matsumoto; H Akedo; H Nakamura
Journal:  Cancer Res       Date:  2001-06-15       Impact factor: 12.701

Review 6.  Protein kinases of the Hippo pathway: regulation and substrates.

Authors:  Joseph Avruch; Dawang Zhou; Julien Fitamant; Nabeel Bardeesy; Fan Mou; Laura Regué Barrufet
Journal:  Semin Cell Dev Biol       Date:  2012-08-09       Impact factor: 7.727

Review 7.  Protein prenylation: molecular mechanisms and functional consequences.

Authors:  F L Zhang; P J Casey
Journal:  Annu Rev Biochem       Date:  1996       Impact factor: 23.643

8.  Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility.

Authors:  Zhongyuan Wang; Yanping Wu; Haifeng Wang; Yangqing Zhang; Lin Mei; Xuexun Fang; Xudong Zhang; Fang Zhang; Hongbo Chen; Ying Liu; Yuyang Jiang; Shengnan Sun; Yi Zheng; Na Li; Laiqiang Huang
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-23       Impact factor: 11.205

9.  Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling.

Authors:  Fa-Xing Yu; Bin Zhao; Nattapon Panupinthu; Jenna L Jewell; Ian Lian; Lloyd H Wang; Jiagang Zhao; Haixin Yuan; Karen Tumaneng; Hairi Li; Xiang-Dong Fu; Gordon B Mills; Kun-Liang Guan
Journal:  Cell       Date:  2012-08-02       Impact factor: 41.582

10.  G protein betagamma subunits regulate cell adhesion through Rap1a and its effector Radil.

Authors:  Syed M Ahmed; Avais M Daulat; Alexandre Meunier; Stephane Angers
Journal:  J Biol Chem       Date:  2010-01-04       Impact factor: 5.157
  10 in total
  7 in total

1.  In Vitro Validation of the Hippo Pathway as a Pharmacological Target for Canine Mammary Gland Tumors.

Authors:  Samantha Guillemette; Charlène Rico; Philippe Godin; Derek Boerboom; Marilène Paquet
Journal:  J Mammary Gland Biol Neoplasia       Date:  2017-08-18       Impact factor: 2.673

2.  MiR-591 functions as tumor suppressor in breast cancer by targeting TCF4 and inhibits Hippo-YAP/TAZ signaling pathway.

Authors:  Xin Huang; Fen Tang; Zeping Weng; Mengyao Zhou; Qing Zhang
Journal:  Cancer Cell Int       Date:  2019-04-24       Impact factor: 5.722

Review 3.  The Role of the Hippo Pathway in Breast Cancer Carcinogenesis, Prognosis, and Treatment: A Systematic Review.

Authors:  Anastasios Kyriazoglou; Michalis Liontos; Roubini Zakopoulou; Maria Kaparelou; Anna Tsiara; Alkistis Maria Papatheodoridi; Rebecca Georgakopoulou; Flora Zagouri
Journal:  Breast Care (Basel)       Date:  2020-05-12       Impact factor: 2.860

4.  Low FAT4 expression is associated with a poor prognosis in gastric cancer patients.

Authors:  Xiaoting Jiang; Zhengchuang Liu; Yingjie Xia; Jungang Luo; Ji Xu; Xujun He; Houquan Tao
Journal:  Oncotarget       Date:  2017-12-26

Review 5.  Interplay Among Metabolism, Epigenetic Modifications, and Gene Expression in Cancer.

Authors:  Miaomiao Huo; Jingyao Zhang; Wei Huang; Yan Wang
Journal:  Front Cell Dev Biol       Date:  2021-12-24

6.  Significant association of YAP1 and HSPC111 proteins with poor prognosis in Chinese gastric cancer patients.

Authors:  Shanshan Huang; Lingling Zhu; Yuan Cao; Li Li; Yongtao Xie; Jun Deng; Jianping Xiong
Journal:  Oncotarget       Date:  2017-05-17

7.  Aberrant super-enhancer-driven oncogene ENC1 promotes the radio-resistance of breast carcinoma.

Authors:  Lin Li; Nan Wang; Mingzhi Zhu; Youyi Xiong; Fang Wang; Guangcheng Guo; Xinxing Wang; Yuanyan Gu
Journal:  Cell Death Dis       Date:  2021-08-06       Impact factor: 8.469
  7 in total

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