Eun Ju Ha1, Jung Hwan Baek2, Jeong Hyun Lee3, Jae Kyun Kim4, Young Jun Choi3, Tae Yon Sung5, Tae Yong Kim6. 1. Department of Radiology, Ajou University School of Medicine, Wonchon-Dong, Yeongtong-Gu, Suwon, 443-380, Korea. 2. Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-Gil, Songpa-gu, Seoul, 138-736, Korea. radbaek@naver.com. 3. Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-Gil, Songpa-gu, Seoul, 138-736, Korea. 4. Department of Radiology, Chung-Ang University College of Medicine, 224-1 Heukseok-dong, Dongjak-gu, Seoul, 156-755, Korea. 5. Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-Gil, Songpa-Gu, Seoul, 138-736, Republic of Korea. 6. Department of Endocrinology and Metabolism, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-Gil, Songpa-Gu, Seoul, 138-736, Republic of Korea.
Abstract
OBJECTIVES: To present the various complications of ultrasound (US)-guided core needle biopsy (CNB) of thyroid lesions in a large patient series. METHODS: From January 2008 to March 2013, 6,169 patients underwent US-guided CNB of 6,687 thyroid nodules at a single institution. We assessed the number and types of major and minor complications, and evaluated the factors associated with complications. RESULTS: Overall, 53 complications were observed in 50 patients (0.81 %), including 4 major and 49 minor complications. The major complications were massive haematoma (n = 2), pseudoaneurysm (n = 1) and voice change leading to disability that lasted for more than 30 days (n = 1). The minor complications were small to moderate haematoma (n = 42), carotid injury (n = 2), voice change that recovered within 30 days (n = 3), tracheal puncture (n = 1) and dysphagia (n = 1). Oedema (n = 12), vertebral puncture (n = 3) and vasovagal reaction (n = 1) were recorded as side effects. The presence of a coprocedure was the only significant factor associated with complications after thyroid CNB (P = 0.023). CONCLUSIONS: US-guided CNB of thyroid lesions was found in a large population to be a safe procedure with a low complication rate. KEY POINTS: • The complication rate after US-guided CNB for thyroid lesions was 0.81 % (50/6,169). • The rate of major complications was 0.06 % (4/6,169). • Vascular injury was the most common complication (47/6,169; 0.76 %). • None of the patients experienced permanent problems resulting from complications.
OBJECTIVES: To present the various complications of ultrasound (US)-guided core needle biopsy (CNB) of thyroid lesions in a large patient series. METHODS: From January 2008 to March 2013, 6,169 patients underwent US-guided CNB of 6,687 thyroid nodules at a single institution. We assessed the number and types of major and minor complications, and evaluated the factors associated with complications. RESULTS: Overall, 53 complications were observed in 50 patients (0.81 %), including 4 major and 49 minor complications. The major complications were massive haematoma (n = 2), pseudoaneurysm (n = 1) and voice change leading to disability that lasted for more than 30 days (n = 1). The minor complications were small to moderate haematoma (n = 42), carotid injury (n = 2), voice change that recovered within 30 days (n = 3), tracheal puncture (n = 1) and dysphagia (n = 1). Oedema (n = 12), vertebral puncture (n = 3) and vasovagal reaction (n = 1) were recorded as side effects. The presence of a coprocedure was the only significant factor associated with complications after thyroid CNB (P = 0.023). CONCLUSIONS: US-guided CNB of thyroid lesions was found in a large population to be a safe procedure with a low complication rate. KEY POINTS: • The complication rate after US-guided CNB for thyroid lesions was 0.81 % (50/6,169). • The rate of major complications was 0.06 % (4/6,169). • Vascular injury was the most common complication (47/6,169; 0.76 %). • None of the patients experienced permanent problems resulting from complications.
Authors: C A Lewis; T E Allen; D R Burke; J F Cardella; S J Citron; P E Cole; A T Drooz; E A Drucker; Z J Haskal; L G Martin; A Van Moore; C D Neithamer; S B Oglevie; K S Rholl; A C Roberts; D Sacks; O Sanchez; A Venbrux; C W Bakal Journal: J Vasc Interv Radiol Date: 1997 May-Jun Impact factor: 3.464
Authors: Zubair W Baloch; Edmund S Cibas; Douglas P Clark; Lester J Layfield; Britt-Marie Ljung; Martha Bishop Pitman; Andrea Abati Journal: Cytojournal Date: 2008-04-07 Impact factor: 2.091
Authors: Young Hen Lee; Jung Hwan Baek; So Lyung Jung; Jin Young Kwak; Ji-hoon Kim; Jung Hee Shin Journal: Korean J Radiol Date: 2015-02-27 Impact factor: 3.500
Authors: Miguel Paja; Jose Luis Del Cura; Rosa Zabala; Igone Korta; Aitziber Ugalde; José I López Journal: Eur Radiol Date: 2019-02-19 Impact factor: 5.315
Authors: Antonio Matrone; Luigi De Napoli; Liborio Torregrossa; Aleksandr Aghababyan; Piermarco Papini; Carlo Enrico Ambrosini; Rosa Cervelli; Clara Ugolini; Fulvio Basolo; Eleonora Molinaro; Rossella Elisei; Gabriele Materazzi Journal: Front Oncol Date: 2022-04-05 Impact factor: 5.738