| Literature DB >> 27311471 |
Serena Manganelli1, Emilio Benfenati2.
Abstract
Read-across has become popular since the introduction of regulations, such as the European REACH regulation. This chapter provides instructions on how to use ToxRead, new freely available software for read-across analysis, and on how to interpret its output predictions for mutagenicity assessments.This tool offers two seminal sources: a set of rules/structural alerts, which may explain the toxicity, and a similarity tool, associated with a large database of chemicals with their properties.Entities:
Keywords: Mutagenicity; REACH; Read-across; Rules; SAR; Structural alerts; ToxRead
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Year: 2016 PMID： 27311471 DOI： 10.1007/978-1-4939-3609-0_13
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745