Literature DB >> 27310907

[What is not searched, it is difficult to find: Chagas' disease].

Luis Briceno1, Walter Mosca1.   

Abstract

A conservative estimation indicates that more than 400 000 Latin American immigrants are living in Italy. Several studies have shown that among these, the prevalence of Chagas disease is between 3.9% and 17%, so it is not unlikely to find a patient with this disease during a cardiology visit. How many patients from Latin America are diagnosed with heart failure in Italy and no one has ever thought about a possible Chagas disease? This brief review describes the situation of the disease in Italy, its characteristics, the etiology of this disease and its treatment. The latter aspect will be discussed considering the recent published results of the BENEFIT study, where it was found that treatment with benznidazole in patients with Chagas' cardiomyopathy is able to reduce significantly the detection of parasites in the blood, but it is not able to prevent clinical deterioration during 5 years of follow-up. The possible implications of these results will be discussed.

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Year:  2016        PMID: 27310907     DOI: 10.1714/2252.24258

Source DB:  PubMed          Journal:  G Ital Cardiol (Rome)        ISSN: 1827-6806


  1 in total

1.  Trypanocidal drugs for late-stage, symptomatic Chagas disease (Trypanosoma cruzi infection).

Authors:  Maite Vallejo; Pedro Pa Reyes; Mireya Martinez Garcia; Alejandro G Gonzalez Garay
Journal:  Cochrane Database Syst Rev       Date:  2020-12-11
  1 in total

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