Literature DB >> 27308616

ATG2B and GSKIP: 2 new genes predisposing to myeloid malignancies.

Isabelle Plo1, Christine Bellanné-Chantelot2, William Vainchenker1.   

Abstract

We have recently identified a 700-kb tandem duplication at locus 14q32.13-q32.2 involving 2 genes, autophagy-related protein 2 homolog B (ATG2B) and GSK3B interacting protein (GSKIP), that increases the predisposition to myeloid malignancies. Here, we discuss the clinical relevance of these findings.

Entities:  

Keywords:  ATG2B; GSKIP; chromosome 14; leukemia; myeloproliferative neoplasm

Year:  2015        PMID： 27308616      PMCID： PMC4905402          DOI： 10.1080/23723556.2015.1094564

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

1.  Inherited predisposition to myeloproliferative neoplasms.

Authors:  Amy V Jones; Nicholas C P Cross
Journal:  Ther Adv Hematol       Date:  2013-08

2.  Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia.

Authors:  Dominique Bluteau; Laure Gilles; Morgane Hilpert; Iléana Antony-Debré; Chloe James; Najet Debili; Valerie Camara-Clayette; Orianne Wagner-Ballon; Veronique Cordette-Lagarde; Thomas Robert; Hugues Ripoche; Patrick Gonin; Sabina Swierczek; Josef Prchal; William Vainchenker; Remi Favier; Hana Raslova
Journal:  Blood       Date:  2011-07-01       Impact factor: 22.113

3.  Mutation of CEBPA in familial acute myeloid leukemia.

Authors:  Matthew L Smith; Jamie D Cavenagh; T Andrew Lister; Jude Fitzgibbon
Journal:  N Engl J Med       Date:  2004-12-02       Impact factor: 91.245

Review 4.  Myeloproliferative neoplasms: JAK2 signaling pathway as a central target for therapy.

Authors:  Florence Pasquier; Xenia Cabagnols; Lise Secardin; Isabelle Plo; William Vainchenker
Journal:  Clin Lymphoma Myeloma Leuk       Date:  2014-09

5.  Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies.

Authors:  Joseph Saliba; Cécile Saint-Martin; Antonio Di Stefano; Gaëlle Lenglet; Caroline Marty; Boris Keren; Florence Pasquier; Véronique Della Valle; Lise Secardin; Gwendoline Leroy; Emna Mahfoudhi; Sarah Grosjean; Nathalie Droin; M'boyba Diop; Philippe Dessen; Sabine Charrier; Alberta Palazzo; Jane Merlevede; Jean-Côme Meniane; Christine Delaunay-Darivon; Pascal Fuseau; Françoise Isnard; Nicole Casadevall; Eric Solary; Najet Debili; Olivier A Bernard; Hana Raslova; Albert Najman; William Vainchenker; Christine Bellanné-Chantelot; Isabelle Plo
Journal:  Nat Genet       Date:  2015-08-17       Impact factor: 38.330

6.  Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms.

Authors:  Chantana Polprasert; Isabell Schulze; Mikkael A Sekeres; Hideki Makishima; Bartlomiej Przychodzen; Naoko Hosono; Jarnail Singh; Richard A Padgett; Xiaorong Gu; James G Phillips; Michael Clemente; Yvonne Parker; Daniel Lindner; Brittney Dienes; Eckhard Jankowsky; Yogen Saunthararajah; Yang Du; Kevin Oakley; Nhu Nguyen; Sudipto Mukherjee; Caroline Pabst; Lucy A Godley; Jane E Churpek; Daniel A Pollyea; Utz Krug; Wolfgang E Berdel; Hans-Ulrich Klein; Martin Dugas; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Kenichi Yoshida; Seishi Ogawa; Carsten Müller-Tidow; Jaroslaw P Maciejewski
Journal:  Cancer Cell       Date:  2015-04-23       Impact factor: 31.743

7.  Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia.

Authors:  Christopher N Hahn; Chan-Eng Chong; Catherine L Carmichael; Ella J Wilkins; Peter J Brautigan; Xiao-Chun Li; Milena Babic; Ming Lin; Amandine Carmagnac; Young K Lee; Chung H Kok; Lucia Gagliardi; Kathryn L Friend; Paul G Ekert; Carolyn M Butcher; Anna L Brown; Ian D Lewis; L Bik To; Andrew E Timms; Jan Storek; Sarah Moore; Meryl Altree; Robert Escher; Peter G Bardy; Graeme K Suthers; Richard J D'Andrea; Marshall S Horwitz; Hamish S Scott
Journal:  Nat Genet       Date:  2011-09-04       Impact factor: 38.330

8.  Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis.

Authors:  Thomas McKerrell; Naomi Park; Thaidy Moreno; Carolyn S Grove; Hannes Ponstingl; Jonathan Stephens; Charles Crawley; Jenny Craig; Mike A Scott; Clare Hodkinson; Joanna Baxter; Roland Rad; Duncan R Forsyth; Michael A Quail; Eleftheria Zeggini; Willem Ouwehand; Ignacio Varela; George S Vassiliou
Journal:  Cell Rep       Date:  2015-02-26       Impact factor: 9.423

9.  Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation.

Authors:  Dominique Bluteau; Alessandra Balduini; Nathalie Balayn; Manuela Currao; Paquita Nurden; Caroline Deswarte; Guy Leverger; Patrizia Noris; Silverio Perrotta; Eric Solary; William Vainchenker; Najet Debili; Remi Favier; Hana Raslova
Journal:  J Clin Invest       Date:  2014-01-16       Impact factor: 14.808

10.  The germline sequence variant rs2736100_C in TERT associates with myeloproliferative neoplasms.

Authors:  A Oddsson; S Y Kristinsson; H Helgason; D F Gudbjartsson; G Masson; A Sigurdsson; A Jonasdottir; A Jonasdottir; H Steingrimsdottir; B Vidarsson; S Reykdal; G I Eyjolfsson; I Olafsson; P T Onundarson; G Runarsson; O Sigurdardottir; A Kong; T Rafnar; P Sulem; U Thorsteinsdottir; K Stefansson
Journal:  Leukemia       Date:  2014-01-30       Impact factor: 11.528
  10 in total
  5 in total

1.  Potentially Functional Variants of ATG16L2 Predict Radiation Pneumonitis and Outcomes in Patients with Non-Small Cell Lung Cancer after Definitive Radiotherapy.

Authors:  Juyi Wen; Hongliang Liu; Lili Wang; Xiaomeng Wang; Ning Gu; Zhensheng Liu; Ting Xu; Daniel R Gomez; Ritsuko Komaki; Zhongxing Liao; Qingyi Wei
Journal:  J Thorac Oncol       Date:  2018-02-15       Impact factor: 15.609

2.  GSKIP-Mediated Anchoring Increases Phosphorylation of Tau by PKA but Not by GSK3beta via cAMP/PKA/GSKIP/GSK3/Tau Axis Signaling in Cerebrospinal Fluid and iPS Cells in Alzheimer Disease.

Authors:  Huey-Jiun Ko; Shean-Jaw Chiou; Yu-Hui Wong; Yin-Hsuan Wang; YunLing Lai; Chia-Hua Chou; Chihuei Wang; Joon-Khim Loh; Ann-Shung Lieu; Jiin-Tsuey Cheng; Yu-Te Lin; Pei-Jung Lu; Ming-Ji Fann; Chi-Ying F Huang; Yi-Ren Hong
Journal:  J Clin Med       Date:  2019-10-21       Impact factor: 4.241

3.  Polymorphisms in autophagy genes are genetic susceptibility factors in glioblastoma development.

Authors:  E Bueno-Martínez; M Lara-Almunia; C Rodríguez-Arias; A Otero-Rodríguez; S Garfias-Arjona; R González-Sarmiento
Journal:  BMC Cancer       Date:  2022-02-05       Impact factor: 4.430

Review 4.  Molecular Pathogenesis in Myeloid Neoplasms with Germline Predisposition.

Authors:  Juehua Gao; Yihua Chen; Madina Sukhanova
Journal:  Life (Basel)       Date:  2021-12-29

5.  Deciphering the evolution of composite-type GSKIP in mitochondria and Wnt signaling pathways.

Authors:  Cheng-Yu Tsai; Shean-Jaw Chiou; Huey-Jiun Ko; Yu-Fan Cheng; Sin-Yi Lin; Yun-Ling Lai; Chen-Yen Lin; Chihuei Wang; Jiin-Tsuey Cheng; Hsin-Fu Liu; Aij-Li Kwan; Joon-Khim Loh; Yi-Ren Hong
Journal:  PLoS One       Date:  2022-01-20       Impact factor: 3.240
  5 in total

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