Literature DB >> 27308612

Collapse of redox homeostasis during aging and stress.

Diogo R Feleciano1, Janine Kirstein1.   

Abstract

Coordination of the protein homeostasis network and redox states in eukaryotic cells is crucial for cellular and organismal fitness. By employing endogenous in vivo redox sensors we demonstrate that the redox state of the ER and cytosol is subject to profound changes upon proteotoxic challenges and during aging.

Keywords:  Chaperones; C.elegans; ER; proteostasis; redox homeostasis

Year:  2015        PMID： 27308612      PMCID： PMC4905398          DOI： 10.1080/23723556.2015.1091060

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  8 in total

1.  Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators.

Authors:  George T Hanson; Robert Aggeler; Devin Oglesbee; Mark Cannon; Roderick A Capaldi; Roger Y Tsien; S James Remington
Journal:  J Biol Chem       Date:  2004-01-13       Impact factor: 5.157

2.  The efficiency of protein compartmentalization into the secretory pathway.

Authors:  Corinna G Levine; Devarati Mitra; Ajay Sharma; Carolyn L Smith; Ramanujan S Hegde
Journal:  Mol Biol Cell       Date:  2004-10-20       Impact factor: 4.138

Review 3.  Protein folding and quality control in the ER.

Authors:  Kazutaka Araki; Kazuhiro Nagata
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-08-01       Impact factor: 10.005

4.  The nascent polypeptide-associated complex is a key regulator of proteostasis.

Authors:  Janine Kirstein-Miles; Annika Scior; Elke Deuerling; Richard I Morimoto
Journal:  EMBO J       Date:  2013-04-19       Impact factor: 11.598

5.  Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging.

Authors:  Anat Ben-Zvi; Elizabeth A Miller; Richard I Morimoto
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-24       Impact factor: 11.205

6.  Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments.

Authors:  Janine Kirstein; Daisuke Morito; Taichi Kakihana; Munechika Sugihara; Anita Minnen; Mark S Hipp; Carmen Nussbaum-Krammer; Prasad Kasturi; F Ulrich Hartl; Kazuhiro Nagata; Richard I Morimoto
Journal:  EMBO J       Date:  2015-07-29       Impact factor: 11.598

7.  Genetically encoded fluorescent indicator for intracellular hydrogen peroxide.

Authors:  Vsevolod V Belousov; Arkady F Fradkov; Konstantin A Lukyanov; Dmitry B Staroverov; Konstantin S Shakhbazov; Alexey V Terskikh; Sergey Lukyanov
Journal:  Nat Methods       Date:  2006-04       Impact factor: 28.547

8.  Spreading of a prion domain from cell-to-cell by vesicular transport in Caenorhabditis elegans.

Authors:  Carmen I Nussbaum-Krammer; Kyung-Won Park; Liming Li; Ronald Melki; Richard I Morimoto
Journal:  PLoS Genet       Date:  2013-03-28       Impact factor: 5.917
  8 in total
  2 in total

Review 1.  N-Acetyl-Cysteine: Modulating the Cysteine Redox Proteome in Neurodegenerative Diseases.

Authors:  Marcos Martinez-Banaclocha
Journal:  Antioxidants (Basel)       Date:  2022-02-18

Review 2.  Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview.

Authors:  Débora Levy; Cadiele Oliana Reichert; Sérgio Paulo Bydlowski
Journal:  Antioxidants (Basel)       Date:  2019-05-02
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.