Literature DB >> 27308583

Mitophagy and deubiquitination in yeast - the power of synthetic quantitative array technology.

Christina Behrendt1, Andreas S Reichert1.   

Abstract

Use of synthetic quantitative array technology led to the identification of positive and negative modulators of rapamycin-induced mitophagy in yeast. The Ubp3-Bre5 deubiquitination complex was shown to inhibit mitophagy but promote other types of autophagy, including ribophagy. We propose an ubiquitin-dependent regulatory switch between different types of autophagy.

Entities:  

Keywords:  Autophagy; Ubp3; deubiquitination; mitophagy; ubiquitination

Year:  2015        PMID： 27308583      PMCID： PMC4905415          DOI： 10.1080/23723556.2015.1038422

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  9 in total

Review 1.  Mechanisms of mitophagy.

Authors:  Richard J Youle; Derek P Narendra
Journal:  Nat Rev Mol Cell Biol       Date:  2011-01       Impact factor: 94.444

Review 2.  Quality control of mitochondria: protection against neurodegeneration and ageing.

Authors:  Takashi Tatsuta; Thomas Langer
Journal:  EMBO J       Date:  2008-01-23       Impact factor: 11.598

3.  Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease.

Authors:  Claudine Kraft; Anna Deplazes; Marc Sohrmann; Matthias Peter
Journal:  Nat Cell Biol       Date:  2008-04-06       Impact factor: 28.824

4.  Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy.

Authors:  Koji Okamoto; Noriko Kondo-Okamoto; Yoshinori Ohsumi
Journal:  Dev Cell       Date:  2009-07       Impact factor: 12.270

5.  Mitophagy in yeast is independent of mitochondrial fission and requires the stress response gene WHI2.

Authors:  Nadine Mendl; Angelo Occhipinti; Matthias Müller; Philipp Wild; Ivan Dikic; Andreas S Reichert
Journal:  J Cell Sci       Date:  2011-03-23       Impact factor: 5.285

Review 6.  A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine.

Authors:  Douglas C Wallace
Journal:  Annu Rev Genet       Date:  2005       Impact factor: 16.830

7.  Synthetic quantitative array technology identifies the Ubp3-Bre5 deubiquitinase complex as a negative regulator of mitophagy.

Authors:  Matthias Müller; Peter Kötter; Christina Behrendt; Elena Walter; Christian Q Scheckhuber; Karl-Dieter Entian; Andreas S Reichert
Journal:  Cell Rep       Date:  2015-02-19       Impact factor: 9.423

8.  Atg32 is a mitochondrial protein that confers selectivity during mitophagy.

Authors:  Tomotake Kanki; Ke Wang; Yang Cao; Misuzu Baba; Daniel J Klionsky
Journal:  Dev Cell       Date:  2009-07       Impact factor: 12.270

9.  A yeast model of the Parkinson's disease-associated protein Parkin.

Authors:  Clara Pereira; Vitor Costa; L Miguel Martins; Lucília Saraiva
Journal:  Exp Cell Res       Date:  2015-02-26       Impact factor: 3.905
  9 in total
  1 in total

Review 1.  Eukaryotic ribosome quality control system: a potential therapeutic target for human diseases.

Authors:  Peng-Yue Zhao; Ren-Qi Yao; Zi-Cheng Zhang; Sheng-Yu Zhu; Yu-Xuan Li; Chao Ren; Xiao-Hui Du; Yong-Ming Yao
Journal:  Int J Biol Sci       Date:  2022-03-14       Impact factor: 6.580
  1 in total

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