Literature DB >> 27308556

Genome-wide DNA methylation profiling in triple-negative breast cancer reveals epigenetic signatures with important clinical value.

Clare Stirzaker1, Elena Zotenko2, Susan J Clark3.   

Abstract

Analysis of cancer methylomes has dramatically changed our concept of the potential of diagnostic and prognostic methylation biomarkers in disease stratification. Through whole-genome methylation capture sequencing of triple-negative breast cancers (TNBCs) we recently identified differentially methylated regions with diagnostic and prognostic value that promise to stratify TNBCs for more personalized management.

Entities:  

Keywords:  Breast cancer; DNA methylation; DNA methylation biomarkers; prognostic biomarkers; triple-negative breast cancer

Year:  2015        PMID： 27308556      PMCID： PMC4845196          DOI： 10.1080/23723556.2015.1038424

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

1.  Molecular stratification of triple-negative breast cancers.

Authors:  Charles M Perou
Journal:  Oncologist       Date:  2011

Review 2.  Mining cancer methylomes: prospects and challenges.

Authors:  Clare Stirzaker; Phillippa C Taberlay; Aaron L Statham; Susan J Clark
Journal:  Trends Genet       Date:  2013-12-21       Impact factor: 11.639

3.  Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value.

Authors:  Clare Stirzaker; Elena Zotenko; Jenny Z Song; Wenjia Qu; Shalima S Nair; Warwick J Locke; Andrew Stone; Nicola J Armstong; Mark D Robinson; Alexander Dobrovic; Kelly A Avery-Kiejda; Kate M Peters; Juliet D French; Sandra Stein; Darren J Korbie; Matt Trau; John F Forbes; Rodney J Scott; Melissa A Brown; Glenn D Francis; Susan J Clark
Journal:  Nat Commun       Date:  2015-02-02       Impact factor: 14.919

4.  Cloning of a mammalian DNA methyltransferase.

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Journal:  Gene       Date:  1988-12-25       Impact factor: 3.688

5.  Colorectal cancer screening with blood-based biomarkers: cost-effectiveness of methylated septin 9 DNA versus current strategies.

Authors:  Uri Ladabaum; John Allen; Michael Wandell; Scott Ramsey
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2013-06-24       Impact factor: 4.254

6.  Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.

Authors:  M Esteller; J Garcia-Foncillas; E Andion; S N Goodman; O F Hidalgo; V Vanaclocha; S B Baylin; J G Herman
Journal:  N Engl J Med       Date:  2000-11-09       Impact factor: 91.245

Review 7.  The epigenomics of cancer.

Authors:  Peter A Jones; Stephen B Baylin
Journal:  Cell       Date:  2007-02-23       Impact factor: 41.582

Review 8.  Gene expression profiling in breast cancer: classification, prognostication, and prediction.

Authors:  Jorge S Reis-Filho; Lajos Pusztai
Journal:  Lancet       Date:  2011-11-19       Impact factor: 79.321

9.  MGMT gene silencing and benefit from temozolomide in glioblastoma.

Authors:  Monika E Hegi; Annie-Claire Diserens; Thierry Gorlia; Marie-France Hamou; Nicolas de Tribolet; Michael Weller; Johan M Kros; Johannes A Hainfellner; Warren Mason; Luigi Mariani; Jacoline E C Bromberg; Peter Hau; René O Mirimanoff; J Gregory Cairncross; Robert C Janzer; Roger Stupp
Journal:  N Engl J Med       Date:  2005-03-10       Impact factor: 91.245

10.  Comprehensive molecular portraits of human breast tumours.

Authors: 
Journal:  Nature       Date:  2012-09-23       Impact factor: 49.962
  10 in total
  8 in total

1.  Emerging Role of Nutri-Epigenetics in Inflammation and Cancer.

Authors:  Paule V Joseph; Sarah K Abey; Wendy A Henderson
Journal:  Oncol Nurs Forum       Date:  2016-11-01       Impact factor: 2.172

2.  Discovery of a Glucocorticoid Receptor (GR) Activity Signature Using Selective GR Antagonism in ER-Negative Breast Cancer.

Authors:  Diana C West; Masha Kocherginsky; Eva Y Tonsing-Carter; D Nesli Dolcen; David J Hosfield; Ricardo R Lastra; Jason P Sinnwell; Kevin J Thompson; Kathleen R Bowie; Ryan V Harkless; Maxwell N Skor; Charles F Pierce; Sarah C Styke; Caroline R Kim; Larischa de Wet; Geoffrey L Greene; Judy C Boughey; Matthew P Goetz; Krishna R Kalari; Liewei Wang; Gini F Fleming; Balázs Györffy; Suzanne D Conzen
Journal:  Clin Cancer Res       Date:  2018-04-10       Impact factor: 12.531

Review 3.  Combined drug therapeutic strategies for the effective treatment of Triple Negative Breast Cancer.

Authors:  Naveen K R Chalakur-Ramireddy; Suresh B Pakala
Journal:  Biosci Rep       Date:  2018-01-30       Impact factor: 3.840

4.  Novel Insights Into Triple-Negative Breast Cancer Prognosis by Comprehensive Characterization of Aberrant Alternative Splicing.

Authors:  Shasha Gong; Zhijian Song; David Spezia-Lindner; Feilong Meng; Tingting Ruan; Guangzhi Ying; Changhong Lai; Qianqian Wu; Yong Liang
Journal:  Front Genet       Date:  2020-06-11       Impact factor: 4.599

5.  A DNA Methylation-Based Test for Breast Cancer Detection in Circulating Cell-Free DNA.

Authors:  Sofia Salta; Sandra P Nunes; Mário Fontes-Sousa; Paula Lopes; Micaela Freitas; Margarida Caldas; Luís Antunes; Fernando Castro; Pedro Antunes; Susana Palma de Sousa; Rui Henrique; Carmen Jerónimo
Journal:  J Clin Med       Date:  2018-11-07       Impact factor: 4.241

6.  A DNA methylation-based liquid biopsy for triple-negative breast cancer.

Authors:  Katrina Cristall; Francois-Clement Bidard; Jean-Yves Pierga; Michael J Rauh; Tatiana Popova; Clara Sebbag; Olivier Lantz; Marc-Henri Stern; Christopher R Mueller
Journal:  NPJ Precis Oncol       Date:  2021-06-16

7.  DNA Methylation Patterns Can Estimate Nonequivalent Outcomes of Breast Cancer with the Same Receptor Subtypes.

Authors:  Min Zhang; Shaojun Zhang; Yanhua Wen; Yihan Wang; Yanjun Wei; Hongbo Liu; Dongwei Zhang; Jianzhong Su; Fang Wang; Yan Zhang
Journal:  PLoS One       Date:  2015-11-09       Impact factor: 3.240

8.  Guanylate-binding protein-1 is a potential new therapeutic target for triple-negative breast cancer.

Authors:  Melissa Quintero; Douglas Adamoski; Larissa Menezes Dos Reis; Carolline Fernanda Rodrigues Ascenção; Krishina Ratna Sousa de Oliveira; Kaliandra de Almeida Gonçalves; Marília Meira Dias; Marcelo Falsarella Carazzolle; Sandra Martha Gomes Dias
Journal:  BMC Cancer       Date:  2017-11-07       Impact factor: 4.430
  8 in total

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