Literature DB >> 27308545

Mutations in ribosomal proteins: Apoptosis, cell competition, and cancer.

Nicholas E Baker1, Abhijit Kale2.   

Abstract

Mutations affecting multiple ribosomal proteins are implicated in cancer. Using genetic mosaics in the fruit fly Drosophila, we describe 3 apoptotic mechanisms that affect Rp/Rp homozygous mutant cells, Rp/+ heterozygous cells, or Rp/+ heterozygous cells in competition with nearby wild type cells, and discuss how apoptosis might be related to cancer predisposition.

Entities:  

Keywords:  Drosophila melanogaster; apoptosis; cancer predisposition; genetic mosaic; ribosomal protein; somatic mutation

Year:  2015        PMID： 27308545      PMCID： PMC4845181          DOI： 10.1080/23723556.2015.1029065

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

1.  Myc-driven endogenous cell competition in the early mammalian embryo.

Authors:  Cristina Clavería; Giovanna Giovinazzo; Rocío Sierra; Miguel Torres
Journal:  Nature       Date:  2013-07-10       Impact factor: 49.962

Review 2.  Cell competition: how to eliminate your neighbours.

Authors:  Marc Amoyel; Erika A Bach
Journal:  Development       Date:  2014-03       Impact factor: 6.868

Review 3.  Cell proliferation in carcinogenesis.

Authors:  S M Cohen; L B Ellwein
Journal:  Science       Date:  1990-08-31       Impact factor: 47.728

4.  An ancient defense system eliminates unfit cells from developing tissues during cell competition.

Authors:  S N Meyer; M Amoyel; C Bergantiños; C de la Cova; C Schertel; K Basler; L A Johnston
Journal:  Science       Date:  2014-12-05       Impact factor: 47.728

5.  Apoptotic mechanisms during competition of ribosomal protein mutant cells: roles of the initiator caspases Dronc and Dream/Strica.

Authors:  A Kale; W Li; C-H Lee; N E Baker
Journal:  Cell Death Differ       Date:  2015-01-23       Impact factor: 15.828

Review 6.  Diamond Blackfan anemia: a disorder of red blood cell development.

Authors:  Steven R Ellis; Jeffrey M Lipton
Journal:  Curr Top Dev Biol       Date:  2008       Impact factor: 4.897

Review 7.  Apoptosome structure, assembly, and procaspase activation.

Authors:  Shujun Yuan; Christopher W Akey
Journal:  Structure       Date:  2013-04-02       Impact factor: 5.006

8.  Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia.

Authors:  Kim De Keersmaecker; Zeynep Kalender Atak; Ning Li; Carmen Vicente; Stephanie Patchett; Tiziana Girardi; Valentina Gianfelici; Ellen Geerdens; Emmanuelle Clappier; Michaël Porcu; Idoya Lahortiga; Rossella Lucà; Jiekun Yan; Gert Hulselmans; Hilde Vranckx; Roel Vandepoel; Bram Sweron; Kris Jacobs; Nicole Mentens; Iwona Wlodarska; Barbara Cauwelier; Jacqueline Cloos; Jean Soulier; Anne Uyttebroeck; Claudia Bagni; Bassem A Hassan; Peter Vandenberghe; Arlen W Johnson; Stein Aerts; Jan Cools
Journal:  Nat Genet       Date:  2012-12-23       Impact factor: 38.330

9.  Identification of RPS14 as a 5q- syndrome gene by RNA interference screen.

Authors:  Benjamin L Ebert; Jennifer Pretz; Jocelyn Bosco; Cindy Y Chang; Pablo Tamayo; Naomi Galili; Azra Raza; David E Root; Eyal Attar; Steven R Ellis; Todd R Golub
Journal:  Nature       Date:  2008-01-17       Impact factor: 49.962

10.  Germline mutation of RPS20, encoding a ribosomal protein, causes predisposition to hereditary nonpolyposis colorectal carcinoma without DNA mismatch repair deficiency.

Authors:  Taina T Nieminen; Marie-Françoise O'Donohue; Yunpeng Wu; Hannes Lohi; Stephen W Scherer; Andrew D Paterson; Pekka Ellonen; Wael M Abdel-Rahman; Satu Valo; Jukka-Pekka Mecklin; Heikki J Järvinen; Pierre-Emmanuel Gleizes; Päivi Peltomäki
Journal:  Gastroenterology       Date:  2014-06-15       Impact factor: 22.682
  10 in total
  5 in total

1.  Ribosomal Protein S12e Has a Distinct Function in Cell Competition.

Authors:  Abhijit Kale; Zhejun Ji; Marianthi Kiparaki; Jorge Blanco; Gerard Rimesso; Stephane Flibotte; Nicholas E Baker
Journal:  Dev Cell       Date:  2018-01-08       Impact factor: 12.270

2.  Mechanisms of cell competition emerging from Drosophila studies.

Authors:  Nicholas E Baker
Journal:  Curr Opin Cell Biol       Date:  2017-06-07       Impact factor: 8.382

3.  Transcriptome and long noncoding RNA sequencing of three extracellular vesicle subtypes released from the human colon cancer LIM1863 cell line.

Authors:  Maoshan Chen; Rong Xu; Hong Ji; David W Greening; Alin Rai; Keiichi Izumikawa; Hideaki Ishikawa; Nobuhiro Takahashi; Richard J Simpson
Journal:  Sci Rep       Date:  2016-12-05       Impact factor: 4.379

4.  Comparative proteomics reveals mechanisms that underlie insecticide resistance in Culex pipiens pallens Coquillett.

Authors:  Chongxing Zhang; Qiqi Shi; Tao Li; Peng Cheng; Xiuxia Guo; Xiao Song; Maoqing Gong
Journal:  PLoS Negl Trop Dis       Date:  2021-03-25

Review 5.  Early Onset Colorectal Cancer: An Emerging Cancer Risk in Patients with Diamond Blackfan Anemia.

Authors:  Jeffrey M Lipton; Christine L S Molmenti; Pooja Desai; Alexander Lipton; Steven R Ellis; Adrianna Vlachos
Journal:  Genes (Basel)       Date:  2021-12-26       Impact factor: 4.096
  5 in total

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