Literature DB >> 27308544

Janus-faced bacterial regulation of epithelial cell death and survival: Association with colon carcinogenesis.

Wei-Ting Kuo1, Tsung-Chun Lee2, Linda Chia-Hui Yu1.   

Abstract

Gut microbiota and lipopolysaccharide (LPS) signaling have been associated with colon cancer development. Our recent findings demonstrated that LPS receptor subunits expressed on colonocytes have antagonistic roles in cell death and tumorigenesis: epithelial toll-like receptor 4 (TLR4) confers resistance to the apoptosis induced by its co-receptor CD14 and contributes to epithelial transition to cancer.

Entities:  

Keywords:  apoptosis; colorectal carcinoma; innate immunity; intestinal homeostasis; lipopolysaccharide

Year:  2015        PMID： 27308544      PMCID： PMC4845180          DOI： 10.1080/23723556.2015.1029064

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

1.  NF-κB directly regulates Fas transcription to modulate Fas-mediated apoptosis and tumor suppression.

Authors:  Feiyan Liu; Kankana Bardhan; Dafeng Yang; Muthusamy Thangaraju; Vadivel Ganapathy; Jennifer L Waller; Georgia B Liles; Jeffrey R Lee; Kebin Liu
Journal:  J Biol Chem       Date:  2012-06-05       Impact factor: 5.157

2.  Phosphatidylcholine-specific phospholipase C (PC-PLC) is required for LPS-mediated macrophage activation through CD14.

Authors:  Joseph Cuschieri; Jens Billgren; Ronald V Maier
Journal:  J Leukoc Biol       Date:  2006-06-05       Impact factor: 4.962

3.  LPS receptor subunits have antagonistic roles in epithelial apoptosis and colonic carcinogenesis.

Authors:  W-T Kuo; T-C Lee; H-Y Yang; C-Y Chen; Y-C Au; Y-Z Lu; L-L Wu; S-C Wei; Y-H Ni; B-R Lin; Y Chen; Y-H Tsai; J T Kung; F Sheu; L-W Lin; L C-H Yu
Journal:  Cell Death Differ       Date:  2015-01-30       Impact factor: 15.828

4.  Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4.

Authors:  Bo Hu; Eran Elinav; Samuel Huber; Carmen J Booth; Till Strowig; Chengcheng Jin; Stephanie C Eisenbarth; Richard A Flavell
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-30       Impact factor: 11.205

5.  RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis.

Authors:  Marius Dannappel; Katerina Vlantis; Snehlata Kumari; Apostolos Polykratis; Chun Kim; Laurens Wachsmuth; Christina Eftychi; Juan Lin; Teresa Corona; Nicole Hermance; Matija Zelic; Petra Kirsch; Marijana Basic; Andre Bleich; Michelle Kelliher; Manolis Pasparakis
Journal:  Nature       Date:  2014-08-17       Impact factor: 49.962

6.  Cell surface phenotype and ultramicroscopic analysis of purified human enterocytes: a possible antigen-presenting cell in the intestine.

Authors:  J M Martín-Villa; S Ferre-López; J C López-Suárez; A Corell; M Pérez-Blas; A Arnaiz-Villena
Journal:  Tissue Antigens       Date:  1997-12

7.  IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer.

Authors:  Florian R Greten; Lars Eckmann; Tim F Greten; Jin Mo Park; Zhi-Wei Li; Laurence J Egan; Martin F Kagnoff; Michael Karin
Journal:  Cell       Date:  2004-08-06       Impact factor: 41.582

8.  Suppression of apoptosis, crypt hyperplasia, and altered differentiation in the colonic epithelia of bak-null mice.

Authors:  Carrie A Duckworth; D Mark Pritchard
Journal:  Gastroenterology       Date:  2008-11-19       Impact factor: 22.682

9.  Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88.

Authors:  Seth Rakoff-Nahoum; Ruslan Medzhitov
Journal:  Science       Date:  2007-07-06       Impact factor: 47.728

10.  Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors.

Authors:  Masayuki Fukata; Anli Chen; Arunan S Vamadevan; Jason Cohen; Keith Breglio; Suneeta Krishnareddy; David Hsu; Ruliang Xu; Noam Harpaz; Andrew J Dannenberg; Kotha Subbaramaiah; Harry S Cooper; Steven H Itzkowitz; Maria T Abreu
Journal:  Gastroenterology       Date:  2007-09-14       Impact factor: 22.682
  10 in total
  1 in total

Review 1.  Impact of microbiota in colorectal carcinogenesis: lessons from experimental models.

Authors:  Linda Chia-Hui Yu; Shu-Chen Wei; Yen-Hsuan Ni
Journal:  Intest Res       Date:  2018-07-27
  1 in total

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