Literature DB >> 27308537

Linking autophagy with inflammation through IRF1 signaling in ER+ breast cancer.

Katherine L Cook1, Jessica L Schwartz-Roberts2, William T Baumann3, Robert Clarke2.   

Abstract

Resistance to antiestrogen therapy remains a critical determinant of mortality in patients affected by ER+ breast cancer. Our previous work identified autophagy and interferon regulatory factor 1 (IRF1) signaling as key regulators of this process. We have recently demonstrated a novel reciprocal interaction between IRF1 and ATG7, linking inflammation and autophagy.

Entities:  

Keywords:  ATG7; IRF1 tumor suppressor; autophagy; breast cancer; estrogen receptor; unfolded protein response

Year:  2015        PMID： 27308537      PMCID： PMC4845173          DOI： 10.1080/23723556.2015.1023928

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

Review 1.  Endoplasmic reticulum stress, the unfolded protein response, autophagy, and the integrated regulation of breast cancer cell fate.

Authors:  Robert Clarke; Katherine L Cook; Rong Hu; Caroline O B Facey; Iman Tavassoly; Jessica L Schwartz; William T Baumann; John J Tyson; Jianhua Xuan; Yue Wang; Anni Wärri; Ayesha N Shajahan
Journal:  Cancer Res       Date:  2012-03-15       Impact factor: 12.701

2.  Hydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer.

Authors:  Katherine L Cook; Anni Wärri; David R Soto-Pantoja; Pamela Ag Clarke; M Idalia Cruz; Alan Zwart; Robert Clarke
Journal:  Clin Cancer Res       Date:  2014-06-15       Impact factor: 12.531

3.  Cancer statistics, 2014.

Authors:  Rebecca Siegel; Jiemin Ma; Zhaohui Zou; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2014-01-07       Impact factor: 508.702

4.  Bortezomib enhances the efficacy of fulvestrant by amplifying the aggregation of the estrogen receptor, which leads to a proapoptotic unfolded protein response.

Authors:  Yuki Ishii; Luena Papa; Urvashi Bahadur; Zhenyu Yue; Julio Aguirre-Ghiso; Toshi Shioda; Samuel Waxman; Doris Germain
Journal:  Clin Cancer Res       Date:  2011-02-03       Impact factor: 12.531

5.  Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate.

Authors:  Jessica L Schwartz-Roberts; Katherine L Cook; Chun Chen; Ayesha N Shajahan-Haq; Margaret Axelrod; Anni Wärri; Rebecca B Riggins; Lu Jin; Bassem R Haddad; Bhaskar V Kallakury; William T Baumann; Robert Clarke
Journal:  Cancer Res       Date:  2015-01-09       Impact factor: 12.701

6.  Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness.

Authors:  Katherine L Cook; Ayesha N Shajahan; Anni Wärri; Lu Jin; Leena A Hilakivi-Clarke; Robert Clarke
Journal:  Cancer Res       Date:  2012-07-01       Impact factor: 12.701

7.  IRF-1 expression induces apoptosis and inhibits tumor growth in mouse mammary cancer cells in vitro and in vivo.

Authors:  Peter K M Kim; Michaele Armstrong; Ye Liu; Peng Yan; Brian Bucher; Brian S Zuckerbraun; Andrea Gambotto; Timothy R Billiar; John H Yim
Journal:  Oncogene       Date:  2004-02-05       Impact factor: 9.867

8.  Interferon-regulatory factor-1 is critical for tamoxifen-mediated apoptosis in human mammary epithelial cells.

Authors:  Michelle L Bowie; Eric C Dietze; Jeffery Delrow; Gregory R Bean; Michelle M Troch; Robin J Marjoram; Victoria L Seewaldt
Journal:  Oncogene       Date:  2004-11-18       Impact factor: 9.867

9.  The Role of Interferon Regulatory Factor-1 (IRF1) in Overcoming Antiestrogen Resistance in the Treatment of Breast Cancer.

Authors:  J L Schwartz; A N Shajahan; R Clarke
Journal:  Int J Breast Cancer       Date:  2011-07-03

10.  International Web-based consultation on priorities for translational breast cancer research.

Authors:  Mitch Dowsett; Aron Goldhirsch; Daniel F Hayes; Hans-Joerg Senn; William Wood; Giuseppe Viale
Journal:  Breast Cancer Res       Date:  2007       Impact factor: 6.466
  10 in total
  2 in total

1.  Interferon regulatory factor-1 regulates cisplatin-induced apoptosis and autophagy in A549 lung cancer cells.

Authors:  Lemeng Zhang; Tianli Cheng; Hua Yang; Jianhua Chen; Xiaoping Wen; Zhou Jiang; Huihuang Yi; Yongzhong Luo
Journal:  Med Oncol       Date:  2022-01-29       Impact factor: 3.064

2.  Identification of tumor antigens and immune subtypes in breast cancer for mRNA vaccine development.

Authors:  Ruo Qi Li; Wei Wang; Lei Yan; Li Ying Song; Xin Guan; Wei Zhang; Jing Lian
Journal:  Front Oncol       Date:  2022-09-26       Impact factor: 5.738
  2 in total

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