| Literature DB >> 2730668 |
T Uchimaru1, S Tsuzuki, K Tanabe, S J Benkovic, K Furukawa, K Taira.
Abstract
The significance of the enol form of the pterin ring in enzymatic reduction of dihydrofolate by DHFR is discussed on the basis of the results of ab initio calculations carried out on the keto/enol tautomers of 6-methyl-7, 8-dihydropterin as the model compound for the natural substrate, dihydrofolate.Entities:
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Year: 1989 PMID： 2730668 DOI： 10.1016/0006-291x(89)91560-x
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575