Literature DB >> 2730651

Characterization of ribonucleolytic activity of angiogenin towards tRNA.

F S Lee1, B L Vallee.   

Abstract

Yeast tRNA is a convenient substrate for the assay of the ribonucleolytic activity of human angiogenin. The optimal pH, [NaCl], and temperature for tRNA cleavage by angiogenin are approximately 6.8, 15-30 mM, and approximately 55 degrees C, respectively, as compared with approximately 8.0, 100-200 mM, and approximately 65 degrees C, respectively, for RNase A. Polyanions and metals both inhibit angiogenin and RNase A but to different extents.

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Year:  1989        PMID： 2730651     DOI： 10.1016/0006-291x(89)91569-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  13 in total

Review 1.  New insights into the role of angiogenin in actin polymerization.

Authors:  Mikhail G Pyatibratov; Alla S Kostyukova
Journal:  Int Rev Cell Mol Biol       Date:  2012       Impact factor: 6.813

2.  Angiogenin promotes tumoral growth and angiogenesis by regulating matrix metallopeptidase-2 expression via the ERK1/2 pathway.

Authors:  M Miyake; S Goodison; A Lawton; E Gomes-Giacoia; C J Rosser
Journal:  Oncogene       Date:  2014-02-24       Impact factor: 9.867

3.  A comparison of the predicted and X-ray structures of angiogenin. Implications for further studies of model building of homologous proteins.

Authors:  S C Allen; K R Acharya; K A Palmer; R Shapiro; B L Vallee; H A Scheraga
Journal:  J Protein Chem       Date:  1994-10

4.  Humanization of immunotoxins.

Authors:  S M Rybak; H R Hoogenboom; H M Meade; J C Raus; D Schwartz; R J Youle
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-15       Impact factor: 11.205

5.  A combined kinetic and modeling study of the catalytic center subsites of human angiogenin.

Authors:  N Russo; K R Acharya; B L Vallee; R Shapiro
Journal:  Proc Natl Acad Sci U S A       Date:  1996-01-23       Impact factor: 11.205

6.  A small-molecule inhibitor of the ribonucleolytic activity of human angiogenin that possesses antitumor activity.

Authors:  Richard Y T Kao; Jeremy L Jenkins; Karen A Olson; Marc E Key; James W Fett; Robert Shapiro
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-12       Impact factor: 11.205

Review 7.  Three decades of research on angiogenin: a review and perspective.

Authors:  Jinghao Sheng; Zhengping Xu
Journal:  Acta Biochim Biophys Sin (Shanghai)       Date:  2015-12-23       Impact factor: 3.848

8.  In lysate RNA digestion provides insights into the angiogenin's specificity towards transfer RNAs.

Authors:  Yasutoshi Akiyama; Yoshihisa Tomioka; Takaaki Abe; Paul Anderson; Pavel Ivanov
Journal:  RNA Biol       Date:  2021-06-04       Impact factor: 4.766

9.  Crystal structures of murine angiogenin-2 and -3-probing 'structure--function' relationships amongst angiogenin homologues.

Authors:  Shalini Iyer; Daniel E Holloway; K Ravi Acharya
Journal:  FEBS J       Date:  2012-12-11       Impact factor: 5.542

Review 10.  The Ribonuclease A Superfamily in Humans: Canonical RNases as the Buttress of Innate Immunity.

Authors:  Patrick Koczera; Lukas Martin; Gernot Marx; Tobias Schuerholz
Journal:  Int J Mol Sci       Date:  2016-08-05       Impact factor: 5.923
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