Literature DB >> 27306127

A comparative study of conventional and liquid-based cervical cytology.

Mehmet Şükrü Budak, Mehmet B Senturk, Cihan Kaya1, Sedat Akgol, Muhammed H Bademkiran, Ali Emre Tahaoğlu, Ayhan Yildirim, Hüseyin Büyükbayram.   

Abstract

OBJECTIVES: The aim of our study is the comparison of the results of conventional smear (CC) technique and liquidbased cytology (LBC) technique used as cervical cancer screening methods.
MATERIAL AND METHODS: The results of 47954 patients submitted to smear screening in our gynecology clinic between January 2008 and December 2014 have been studied. The smear results have been divided into two groups CC and LBC according to the technique used.
RESULTS: When considering the distribution within CC group, the results were as follows: intraepithelial cell abnormalities 2,0% (n=619), insufficient sample for analysis 2,1% (n=660), Atypical squamous cells of undetermined significance (ASC-US) 1.8% (n=554), Low grade squamous intraepithelial lesion (LGSIL) 0.1% (n=35), High grade squamous intraepithelial lesion (HGSIL) 0.1% (n=16), Atypical squamous cells - cannot exclude HGSIL (ASC-H) 0.029% (n=9), Atypical glandular cells- not other wise specified (AGC-NOS) 0.012% (n=4), squamous carcinoma 0.003% (n=1). When considering the distribution in LBC group, the results were as follows: intraepithelial cell abnormalities2.1% (n=357), insufficient sample for analysis 0.9% (n=144), ASC-US 1.8% (n=296), LGSIL 0.2% (n=38), HGSIL 0.1% (n=8), ASC-H 0.1% (n=10), AGC-NOS 0.017% (n=3), squamous carcinoma 0.011% (n=2).
CONCLUSIONS: Although the rates of epithelial cell abnormalities are similar for both tests, LSIL results are more frequently observed in LBC technique. In LBC technique, the number of insufficient sample for analysis is quite low compared to CC group and thus constitutes an advantage.

Entities:  

Mesh:

Year:  2016        PMID: 27306127     DOI: 10.17772/gp/60980

Source DB:  PubMed          Journal:  Ginekol Pol        ISSN: 0017-0011            Impact factor:   1.232


  3 in total

1.  The value of p16INK4a immunostaining for high-grade squamous intraepithelial lesions in human papillomavirus-negative patients.

Authors:  Dai Zhang; Jie Song; Xiaosong Zhang; Hui Bi
Journal:  BMC Womens Health       Date:  2022-04-27       Impact factor: 2.742

2.  HPV Genotype Specific and Age Stratified Immediate Prevalence of Cervical Precancers and Cancers in Women with NILM/hrHPV+: A Single Center Retrospective Study of 26,228 Cases.

Authors:  Qin Liu; Xin Zhou; Xiaofei Zhang; Amanda Louise Strickland; Wenxin Zheng; Hao Chen; Feng Zhou
Journal:  Cancer Manag Res       Date:  2021-09-02       Impact factor: 3.989

3.  Clinical study on primary screening of oral cancer and precancerous lesions by oral cytology.

Authors:  Shintaro Sukegawa; Sawako Ono; Keisuke Nakano; Kiyofumi Takabatake; Hotaka Kawai; Hitoshi Nagatsuka; Yoshihiko Furuki
Journal:  Diagn Pathol       Date:  2020-09-10       Impact factor: 2.644

  3 in total

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