Literature DB >> 27306074

The Next Wave of Biological Agents for the Treatment of IBD: Evidence from Cochrane Reviews.

Reena Khanna1, Nilesh Chande, Séverine Vermeire, William J Sandborn, Claire E Parker, Brian G Feagan.   

Abstract

Multiple new biological treatments for Crohn's disease and ulcerative colitis are becoming available. Specifically, vedolizumab and ustekinumab are monoclonal antibodies that target molecular pathways relevant to disease pathogenesis. What can Cochrane reviews tell us about the efficacy, safety, and immunogenicity of these new agents? A Cochrane inflammatory bowel disease group symposium held at the 2015 Digestive Diseases Week annual meeting addressed these questions. This article reviews the data presented at that session.

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Year:  2016        PMID: 27306074     DOI: 10.1097/MIB.0000000000000808

Source DB:  PubMed          Journal:  Inflamm Bowel Dis        ISSN: 1078-0998            Impact factor:   5.325


  3 in total

1.  The Present and Future of Inflammatory Bowel Disease Treatment.

Authors:  William J Sandborn
Journal:  Gastroenterol Hepatol (N Y)       Date:  2016-07

Review 2.  Chronic Rhinosinusitis and the Evolving Understanding of Microbial Ecology in Chronic Inflammatory Mucosal Disease.

Authors:  Michael Hoggard; Brett Wagner Mackenzie; Ravi Jain; Michael W Taylor; Kristi Biswas; Richard G Douglas
Journal:  Clin Microbiol Rev       Date:  2017-01       Impact factor: 26.132

3.  Inflammatory Endotypes and Microbial Associations in Chronic Rhinosinusitis.

Authors:  Michael Hoggard; Sharon Waldvogel-Thurlow; Melissa Zoing; Kevin Chang; Fiona J Radcliff; Brett Wagner Mackenzie; Kristi Biswas; Richard G Douglas; Michael W Taylor
Journal:  Front Immunol       Date:  2018-09-19       Impact factor: 7.561

  3 in total

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