Usman Bashir1, Muhammad Musib Siddique1, Emma Mclean2, Vicky Goh1,3, Gary J Cook1,4. 1. 1 Department of Cancer Imaging, Division of Imaging Sciences and Biomedical Engineering, King's College London, London SE1 7EH, UK. 2. 2 Department of Histopathology, Guy's and St. Thomas' Hospitals, London, UK. 3. 3 Department of Radiology, Guy's and St. Thomas' Hospitals, London, UK. 4. 4 PET Imaging Centre, Division of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Abstract
OBJECTIVE: Texture analysis involves the mathematic processing of medical images to derive sets of numeric quantities that measure heterogeneity. Studies on lung cancer have shown that texture analysis may have a role in characterizing tumors and predicting patient outcome. This article outlines the mathematic basis of and the most recent literature on texture analysis in lung cancer imaging. We also describe the challenges facing the clinical implementation of texture analysis. CONCLUSION: Texture analysis of lung cancer images has been applied successfully to FDG PET and CT scans. Different texture parameters have been shown to be predictive of the nature of disease and of patient outcome. In general, it appears that more heterogeneous tumors on imaging tend to be more aggressive and to be associated with poorer outcomes and that tumor heterogeneity on imaging decreases with treatment. Despite these promising results, there is a large variation in the reported data and strengths of association.
OBJECTIVE: Texture analysis involves the mathematic processing of medical images to derive sets of numeric quantities that measure heterogeneity. Studies on lung cancer have shown that texture analysis may have a role in characterizing tumors and predicting patient outcome. This article outlines the mathematic basis of and the most recent literature on texture analysis in lung cancer imaging. We also describe the challenges facing the clinical implementation of texture analysis. CONCLUSION: Texture analysis of lung cancer images has been applied successfully to FDG PET and CT scans. Different texture parameters have been shown to be predictive of the nature of disease and of patient outcome. In general, it appears that more heterogeneous tumors on imaging tend to be more aggressive and to be associated with poorer outcomes and that tumor heterogeneity on imaging decreases with treatment. Despite these promising results, there is a large variation in the reported data and strengths of association.
Authors: Sarah M Ryan; Tasha E Fingerlin; Margaret Mroz; Briana Barkes; Nabeel Hamzeh; Lisa A Maier; Nichole E Carlson Journal: Eur Respir J Date: 2019-08-29 Impact factor: 16.671
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Authors: Yongfeng Gao; Zhengrong Liang; Hao Zhang; Jie Yang; John Ferretti; Thomas Bilfinger; Kavitha Yaddanapudi; Mark Schweitzer; Priya Bhattacharji; William Moore Journal: IEEE Trans Radiat Plasma Med Sci Date: 2019-12-04