| Literature DB >> 27304493 |
Matthias H Tschöp1, Michael Stumvoll2, Michael Ristow3.
Abstract
Type 2 diabetes is associated with increased risk of malignancies, whereas antidiabetic interventions like physical exercise or metformin reduce cancer incidence. A recent publication shows that one diabetes treatment approach, namely incretin-related DPP4 inhibitors, increases metastatic capacity by activating the antioxidant transcription factor NRF2 to decrease reactive oxygen species (ROS) levels.Entities:
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Year: 2016 PMID： 27304493 DOI： 10.1016/j.cmet.2016.05.017
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287