| Literature DB >> 27303168 |
Hyun Ju Lee1, Gyeong Hun Park1, Sung Eun Chang1, Mi Woo Lee1, Jee Ho Choi1, Kee Chan Moon1.
Abstract
Merkel cell carcinoma is a rare aggressive primary cutaneous neuroendocrine skin cancer arising from the basal epidermis. Although the majority of patients with non-melanoma skin cancer are cured by local treatment, patients with Merkel cell carcinoma have a poor outcome characterized by locoregional and distant relapse. No standard treatment protocol for Merkel cell carcinoma exists. But, there is mounting evidence that combined treatment, incorporating adjuvant radiotherapy, improves the outcome (locoregional control and disease-free survival) compared with surgery alone in most patients. Herein we report a case of Merkel cell carcinoma treated with wide local excision and post-operative radiotherapy.Entities:
Keywords: Adjuvant radiotherapy; Merkel cell carcinoma; Wide local excision
Year: 2008 PMID: 27303168 PMCID: PMC4904060 DOI: 10.5021/ad.2008.20.2.90
Source DB: PubMed Journal: Ann Dermatol ISSN: 1013-9087 Impact factor: 1.444