Literature DB >> 27303168

A Case of Merkel Cell Carcinoma: Treated with Wide Excision and Adjuvant Radiotherapy.

Hyun Ju Lee1, Gyeong Hun Park1, Sung Eun Chang1, Mi Woo Lee1, Jee Ho Choi1, Kee Chan Moon1.   

Abstract

Merkel cell carcinoma is a rare aggressive primary cutaneous neuroendocrine skin cancer arising from the basal epidermis. Although the majority of patients with non-melanoma skin cancer are cured by local treatment, patients with Merkel cell carcinoma have a poor outcome characterized by locoregional and distant relapse. No standard treatment protocol for Merkel cell carcinoma exists. But, there is mounting evidence that combined treatment, incorporating adjuvant radiotherapy, improves the outcome (locoregional control and disease-free survival) compared with surgery alone in most patients. Herein we report a case of Merkel cell carcinoma treated with wide local excision and post-operative radiotherapy.

Entities:  

Keywords:  Adjuvant radiotherapy; Merkel cell carcinoma; Wide local excision

Year:  2008        PMID: 27303168      PMCID: PMC4904060          DOI: 10.5021/ad.2008.20.2.90

Source DB:  PubMed          Journal:  Ann Dermatol        ISSN: 1013-9087            Impact factor:   1.444


  12 in total

1.  Merkel cell carcinoma occurring in renal transplant patients.

Authors:  A Urbatsch; W M Sams; M M Urist; R Sturdivant
Journal:  J Am Acad Dermatol       Date:  1999-08       Impact factor: 11.527

2.  A meta-analysis of the prognostic significance of sentinel lymph node status in Merkel cell carcinoma.

Authors:  Khosrow Mehrany; Clark C Otley; Roger H Weenig; P Kim Phillips; Randall K Roenigk; Tri H Nguyen
Journal:  Dermatol Surg       Date:  2002-02       Impact factor: 3.398

Review 3.  Merkel cell carcinoma.

Authors:  Michael Howard Swann; Jaeyoung Yoon
Journal:  Semin Oncol       Date:  2007-02       Impact factor: 4.929

4.  Lymphatic mapping for Merkel cell carcinoma.

Authors:  T Pfeifer; H Weinberg; M S Brady
Journal:  J Am Acad Dermatol       Date:  1997-10       Impact factor: 11.527

Review 5.  Unusual presentation of a Merkel cell carcinoma.

Authors:  T G Chiarelli; J M Grant-Kels; J R Sporn; W N Rezuke; J D Whalen
Journal:  J Am Acad Dermatol       Date:  2000-02       Impact factor: 11.527

Review 6.  Merkel cell carcinoma arising in the head and neck: optimizing therapy.

Authors:  B D Lawenda; J K Thiringer; R D Foss; P A Johnstone
Journal:  Am J Clin Oncol       Date:  2001-02       Impact factor: 2.339

7.  Merkel cell carcinoma: improved outcome with adjuvant radiotherapy.

Authors:  Michael J Veness; Lakmalie Perera; Junie McCourt; Jennifer Shannon; T Michael Hughes; Gary J Morgan; Val Gebski
Journal:  ANZ J Surg       Date:  2005-05       Impact factor: 1.872

8.  The natural history and management of Merkel cell carcinoma of the skin: a review of 22 patients treated at the Royal Marsden Hospital.

Authors:  P Savage; D Constenla; C Fisher; J M Thomas; M E Gore
Journal:  Clin Oncol (R Coll Radiol)       Date:  1997       Impact factor: 4.126

9.  Merkel cell carcinoma of the head and neck: effect of surgical excision and radiation on recurrence and survival.

Authors:  A M Gillenwater; A C Hessel; W H Morrison; M Burgess; E G Silva; D Roberts; H Goepfert
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2001-02

Review 10.  Merkel cell carcinoma (primary cutaneous neuroendocrine carcinoma): an overview on management.

Authors:  Michael J Veness
Journal:  Australas J Dermatol       Date:  2006-08       Impact factor: 2.875

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