Literature DB >> 27303121

SDH with Bleeding Diathesis-a Management Protocol.

Gurneet Singh Sawhney1, Cecil R Ross2, Manmeet Singh Chhabra1, Vineesh K Varghese1, Ashish Tiwari1, Ashis K Chand1.   

Abstract

Chronic subdural hematoma (SDH) is one of the leading causes of morbidity and mortality in elderly. Patients taking antiplatelets and/or anticoagulants have increased risk of bleeding during the perioperative period. Precise dose blood products and specific surgical technique have been effective in preventing hemorrhagic complications perioperatively. From Jan 2010 to Dec 2012, 25 patients who were on antiplatelets and/or oral anticoagulants underwent emergency surgery for chronic or acute on chronic SDH. Patients were divided into three groups: group I-patients on antiplatelets, group II-patients on oral anticoagulants, and group III-patients taking both. Of these, 21 patients underwent minicraniotomy with microsurgical membranectomy and 4 patients underwent burr hole craniostomy. Random donor platelet concentrate (RDPC) and fresh frozen plasma (FFP) were used depending on whether patient was on antiplatelets or oral anticoagulants. Results were evaluated on the basis of ease of intraoperative hemostasis, incidence of rebleeding in postoperative period, postoperative imaging, and reversal of neurological deficits. Group I, group II, and group III had 16, 4, and 5 patients, respectively. Group I received a mean of 7 units of RDPC. Group II received a mean of 4 units of FFP. Group III received a mean of 7 units of RDPC and 4 units FFPs. There was no problem with intraoperative hemostasis and no incidence of rebleeding. We suggest specific dose protocol for reversal of antiplatelet and anticoagulant effect and specific surgical procedure in preventing intraoperative bleeding and postoperative rebleeding in the above group of patients.

Entities:  

Keywords:  Anticoagulants; Antiplatelets; Emergency; Minicraniotomy; Protocol; SDH

Year:  2015        PMID: 27303121      PMCID: PMC4875899          DOI: 10.1007/s12262-015-1331-7

Source DB:  PubMed          Journal:  Indian J Surg        ISSN: 0973-9793            Impact factor:   0.656


  17 in total

Review 1.  Emergency reversal of antiplatelet agents in patients presenting with an intracranial hemorrhage: a clinical review.

Authors:  Peter G Campbell; Anish Sen; Sanjay Yadla; Pascal Jabbour; Jack Jallo
Journal:  World Neurosurg       Date:  2010 Aug-Sep       Impact factor: 2.104

2.  Clinical analysis of risk factors related to recurrent chronic subdural hematoma.

Authors:  Byung-Soo Ko; Jung-Kil Lee; Bo-Ra Seo; Sung-Jun Moon; Jae-Hyoo Kim; Soo-Han Kim
Journal:  J Korean Neurosurg Soc       Date:  2008-01-20

3.  Chronic subdural hematoma: surgical treatment and outcome in 104 patients.

Authors:  R I Ernestus; P Beldzinski; H Lanfermann; N Klug
Journal:  Surg Neurol       Date:  1997-09

4.  Association of aspirin use with major bleeding in patients with and without diabetes.

Authors:  Giorgia De Berardis; Giuseppe Lucisano; Antonio D'Ettorre; Fabio Pellegrini; Vito Lepore; Gianni Tognoni; Antonio Nicolucci
Journal:  JAMA       Date:  2012-06-06       Impact factor: 56.272

5.  Chronic subdural haematoma: a review of 114 cases.

Authors:  M M Cameron
Journal:  J Neurol Neurosurg Psychiatry       Date:  1978-09       Impact factor: 10.154

6.  Risk of bleeding with single, dual, or triple therapy with warfarin, aspirin, and clopidogrel in patients with atrial fibrillation.

Authors:  Morten L Hansen; Rikke Sørensen; Mette T Clausen; Marie Louise Fog-Petersen; Jakob Raunsø; Niels Gadsbøll; Gunnar H Gislason; Fredrik Folke; Søren S Andersen; Tina K Schramm; Steen Z Abildstrøm; Henrik E Poulsen; Lars Køber; Christian Torp-Pedersen
Journal:  Arch Intern Med       Date:  2010-09-13

7.  The pharmacology and management of the vitamin K antagonists: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.

Authors:  Jack Ansell; Jack Hirsh; Leon Poller; Henry Bussey; Alan Jacobson; Elaine Hylek
Journal:  Chest       Date:  2004-09       Impact factor: 9.410

8.  [Chronic subdural hematoma with bleeding tendency; clinical analysis of 11 surgical cases].

Authors:  M Sato; Y Endo; S Takahagi; T Sasaki; N Kodama
Journal:  No Shinkei Geka       Date:  1995-01

9.  Various surgical treatments of chronic subdural hematoma and outcome in 172 patients: is membranectomy necessary?

Authors:  Jin-Yul Lee; Heinrich Ebel; Ralf-Ingo Ernestus; Norfrid Klug
Journal:  Surg Neurol       Date:  2004-06

10.  Transfusion of fresh frozen plasma in non-bleeding ICU patients--TOPIC trial: study protocol for a randomized controlled trial.

Authors:  Marcella C A Müller; Evert de Jonge; M Sesmu Arbous; Angelique M E Spoelstra-de Man; Atilla Karakus; Margreeth B Vroom; Nicole P Juffermans
Journal:  Trials       Date:  2011-12-23       Impact factor: 2.279

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.