PURPOSE: To determine the surgical and oncologic outcomes after major liver surgery for colorectal liver metastases (CRLM) at a Dutch University Hospital. PATIENTS AND METHODS: Consecutive patients with CRLM who had undergone major liver resection, defined as ≥ 4 liver segments, between January 2000 and December 2015 were identified from a prospectively maintained database. RESULTS: Major liver surgery was performed in 117 patients. Of these, 26 patients had undergone formal extended left or right hemihepatectomy. Ninety-day postoperative mortality was 8%. Major postoperative complications occurred in 27% of patients; these adverse events were more common in the extended hemihepatectomy group. Median disease-free survival was 11 months and median overall survival 44 months. CONCLUSION: Major liver surgery, including formal extended hemihepatectomy, is associated with significant operative morbidity and mortality but can confer prolonged overall survival for patients with CRLM. Copyright Â
PURPOSE: To determine the surgical and oncologic outcomes after major liver surgery for colorectal liver metastases (CRLM) at a Dutch University Hospital. PATIENTS AND METHODS: Consecutive patients with CRLM who had undergone major liver resection, defined as ≥ 4 liver segments, between January 2000 and December 2015 were identified from a prospectively maintained database. RESULTS: Major liver surgery was performed in 117 patients. Of these, 26 patients had undergone formal extended left or right hemihepatectomy. Ninety-day postoperative mortality was 8%. Major postoperative complications occurred in 27% of patients; these adverse events were more common in the extended hemihepatectomy group. Median disease-free survival was 11 months and median overall survival 44 months. CONCLUSION: Major liver surgery, including formal extended hemihepatectomy, is associated with significant operative morbidity and mortality but can confer prolonged overall survival for patients with CRLM. Copyright Â
Authors: Xu-Feng Zhang; Fabio Bagante; Jeffery Chakedis; Dimitrios Moris; Eliza W Beal; Matthew Weiss; Irinel Popescu; Hugo P Marques; Luca Aldrighetti; Shishir K Maithel; Carlo Pulitano; Todd W Bauer; Feng Shen; George A Poultsides; Oliver Soubrane; Guillaume Martel; B Groot Koerkamp; Alfredo Guglielmi; Endo Itaru; Timothy M Pawlik Journal: J Gastrointest Surg Date: 2017-07-25 Impact factor: 3.452
Authors: Elske C Gootjes; Eric P van der Stok; Cornelis Verhoef; Henk M W Verheul; Tineke E Buffart; Lotte Bakkerus; Mariette Labots; Barbara M Zonderhuis; Jurriaan B Tuynman; Martijn R Meijerink; Peter M van de Ven; Cornelis J A Haasbeek; Albert J Ten Tije; Jan-Willem B de Groot; Mathijs P Hendriks; Esther van Meerten; Joost J M E Nuyttens; Dirk J Grunhagen Journal: Oncologist Date: 2020-06-16
Authors: Alexander Fischer; Juri Fuchs; Christos Stravodimos; Ulf Hinz; Adrian Billeter; Markus W Büchler; Arianeb Mehrabi; Katrin Hoffmann Journal: BMC Surg Date: 2020-11-30 Impact factor: 2.102