Literature DB >> 27297033

PGMA-Based Star-Like Polycations with Plentiful Hydroxyl Groups Act as Highly Efficient miRNA Delivery Nanovectors for Effective Applications in Heart Diseases.

Rui-Quan Li1, Yina Wu2, Ying Zhi2, Xinchao Yang1, Yulin Li2, Fu-Jian Xua1, Jie Du2.   

Abstract

Poly(glycidyl methacrylate)-based star-like polycations with rich hydrophilic hydroxyl groups can efficiently transfer miRNA into primary cardiac fibroblasts for effective applications in cardiac diseases, such as inhibition of cardiac fibrosis and hypertrophy.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  PGEA; fibrosis; heart diseases; hypertrophy; miRNA

Mesh：

Substances：

Year:  2016        PMID： 27297033     DOI： 10.1002/adma.201602319

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  11 in total

1.  Development of switchable polymers to address the dilemma of stability and cargo release in polycationic nucleic acid carriers.

Authors:  Yilong Cheng; Drew L Sellers; James-Kevin Y Tan; David J Peeler; Philip J Horner; Suzie H Pun
Journal:  Biomaterials       Date:  2017-03-01       Impact factor: 12.479

2.  Response by Du et al to Letter Regarding Article, "Cardiac Fibroblast-Specific Activating Transcription Factor 3 Protects Against Heart Failure by Suppressing MAP2K3-p38 Signaling".

Authors:  Jie Du; Xin-Liang Ma; Yulin Li; Boya Chen
Journal:  Circulation       Date:  2017-11-21       Impact factor: 29.690

3.  Hydrogel-mediated delivery of microRNA-92a inhibitor polyplex nanoparticles induces localized angiogenesis.

Authors:  Fatemeh Radmanesh; Hamid Sadeghi Abandansari; Mohammad Hossein Ghanian; Sara Pahlavan; Fahimeh Varzideh; Saeed Yakhkeshi; Mehdi Alikhani; Sharif Moradi; Thomas Braun; Hossein Baharvand
Journal:  Angiogenesis       Date:  2021-03-19       Impact factor: 10.658

4.  Rod-Shaped Active Drug Particles Enable Efficient and Safe Gene Delivery.

Authors:  Xiaofei Xin; Xue Pei; Xin Yang; Yaqi Lv; Li Zhang; Wei He; Lifang Yin
Journal:  Adv Sci (Weinh)       Date:  2017-09-05       Impact factor: 16.806

Review 5.  Advances in the delivery of RNA therapeutics: from concept to clinical reality.

Authors:  James C Kaczmarek; Piotr S Kowalski; Daniel G Anderson
Journal:  Genome Med       Date:  2017-06-27       Impact factor: 11.117

6.  Effective Delivery of Hypertrophic miRNA Inhibitor by Cholesterol-Containing Nanocarriers for Preventing Pressure Overload Induced Cardiac Hypertrophy.

Authors:  Ying Zhi; Chen Xu; Dandan Sui; Jie Du; Fu-Jian Xu; Yulin Li
Journal:  Adv Sci (Weinh)       Date:  2019-04-06       Impact factor: 16.806

7.  Multifunctional cationic nanosystems for nucleic acid therapy of thoracic aortic dissection.

Authors:  Chen Xu; Yanzhenzi Zhang; Ke Xu; Jing-Jun Nie; Bingran Yu; Sijin Li; Gang Cheng; Yulin Li; Jie Du; Fu-Jian Xu
Journal:  Nat Commun       Date:  2019-07-18       Impact factor: 14.919

8.  Reversible Treatment of Pressure Overload-Induced Left Ventricular Hypertrophy through Drd5 Nucleic Acid Delivery Mediated by Functional Polyaminoglycoside.

Authors:  Xiaoliang Jiang; Meiyu Shao; Xue Liu; Xing Liu; Xu Zhang; Yuming Wang; Kunlun Yin; Shuiyun Wang; Yang Hu; Pedro A Jose; Zhou Zhou; Fu-Jian Xu; Zhiwei Yang
Journal:  Adv Sci (Weinh)       Date:  2021-01-06       Impact factor: 16.806

Review 9.  Biomaterial-assisted biotherapy: A brief review of biomaterials used in drug delivery, vaccine development, gene therapy, and stem cell therapy.

Authors:  Xuejiao Han; Aqu Alu; Hongmei Liu; Yi Shi; Xiawei Wei; Lulu Cai; Yuquan Wei
Journal:  Bioact Mater       Date:  2022-01-19

10.  The protein corona modulates the inflammation inhibition by cationic nanoparticles via cell-free DNA scavenging.

Authors:  Xingliang Liu; Huiyi Liang; Yanzi Yan; Jingjiao Wu; Massimo Bottini; Lixin Liu; Yongming Chen
Journal:  Bioact Mater       Date:  2021-11-03
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