Literature DB >> 27294270

[Clinical diagnosis and drug therapy of elderly patients with schizophrenia : A restrospective analysis of data in a department of old age psychiatry].

Christian Jagsch1, Gabriele Dietmaier2, Maximilian Jagsch3, Martin Kurz4.   

Abstract

BACKGROUND: The objective of this study was to survey the consistency of the clinical diagnostics and the psychopharmacological treatment of schizophrenia and delusional disorders suffered by older persons. A further aspect was to record significant clinical differences and also similarities between the patient groups in care, matching with the criteria of ICD 10 for schizophrenia (F20), persistent delusional disorders (F22) and schizoaffective disorder (F25).
METHODS: Retrospective analysis with reference to the manually and electronically recorded patient medical records of an acute case care ward for geriatric psychiatry and psychotherapy.
RESULTS: During the assessment period 210 patients over the age of 65 years were included consecutively in the study (F20 - 64 patients, F22 - 78 patients, F25 - 64 patients, 4 patients died). Ignoring the fact that many of the patients were admitted without a diagnosis, the diagnostic classification of the referring doctor, above all those made by general practitioners, proved to be very consistent for the groups F20 and F25. In the group F22 diagnoses, however, up to almost one half of the referred patients were incorrectly admitted with an F20 diagnosis. The patients included in group F22 formed a heterogeneous group, or a melting pot for various sub-groups, with the common shared characteristic of being comprised of persons suffering from a delusional disorder. These differed from the other two groups in the following attributes: the patients were either older or very old persons, they were mostly receiving inpatient treatment for the first time and subsequently had fewer re-admissions. They also suffered more frequently from both psychiatric and somatic comorbidities; furthermore they included elderly people who had suffered from learning deficiencies or borderline intellectual deficiencies throughout their earlier lives. The patients in groups F20 and F25 differed primarily only in terms of their psychiatric medication, with significantly more mood stabilizer prescribed in the F25 group. Patients in all three groups frequently received tranquilisers during the day and sedatives in the evening, atypical antipsychotics were prescribed in the great majority of cases.
CONCLUSION: The referral diagnoses of patients suffering from many years of schizophrenic type illnesses were largely in compliance with the diagnostic criteria, a much more difficult issue for the referring doctors was the allocation of patients with a first occurrence of delusional symptoms. Those patients who were allocated to the diagnostic group schizophrenia differed significantly from patients from the group with delusional disorders.

Entities:  

Keywords:  Clinical diagnostic; Delusional disorder; Elderly patients; Psychotropic drugs; Schizophrenia

Mesh:

Substances:

Year:  2016        PMID: 27294270     DOI: 10.1007/s40211-016-0183-0

Source DB:  PubMed          Journal:  Neuropsychiatr        ISSN: 0948-6259


  17 in total

1.  Delusional disorders--are they simply paranoid schizophrenia?

Authors:  Andreas Marneros; Frank Pillmann; Tobias Wustmann
Journal:  Schizophr Bull       Date:  2010-11-15       Impact factor: 9.306

Review 2.  Schizophrenia and older adults. An overview: directions for research and policy.

Authors:  C I Cohen; G D Cohen; K Blank; C Gaitz; I R Katz; A Leuchter; G Maletta; B Meyers; K Sakauye; C Shamoian
Journal:  Am J Geriatr Psychiatry       Date:  2000       Impact factor: 4.105

3.  Schizophrenia spectrum disorders in later life: prevalence and distribution of age at onset and sex in a dutch catchment area.

Authors:  Paul D Meesters; Lieuwe de Haan; Hannie C Comijs; Max L Stek; Maureen M J Smeets-Janssen; Marjan R Weeda; Piet Eikelenboom; Johannes H Smit; Aartjan T F Beekman
Journal:  Am J Geriatr Psychiatry       Date:  2012-01       Impact factor: 4.105

4.  Very late-onset schizophrenia-like psychosis: clinical and imaging characteristics in comparison with elderly patients with schizophrenia.

Authors:  Yoram Barak; Dov Aizenberg; Ilona Mirecki; Doron Mazeh; Anat Achiron
Journal:  J Nerv Ment Dis       Date:  2002-11       Impact factor: 2.254

Review 5.  Late-onset schizophrenia and very-late-onset schizophrenia-like psychosis: an international consensus. The International Late-Onset Schizophrenia Group.

Authors:  R Howard; P V Rabins; M V Seeman; D V Jeste
Journal:  Am J Psychiatry       Date:  2000-02       Impact factor: 18.112

Review 6.  New wine in old bottle: late-life psychosis.

Authors:  Alana Iglewicz; Thomas W Meeks; Dilip V Jeste
Journal:  Psychiatr Clin North Am       Date:  2011-06

7.  Symptomatic remission and associated factors in a catchment area based population of older patients with schizophrenia.

Authors:  Paul D Meesters; Hannie C Comijs; Lieuwe de Haan; Johannes H Smit; Piet Eikelenboom; Aartjan T F Beekman; Max L Stek
Journal:  Schizophr Res       Date:  2011-03       Impact factor: 4.939

Review 8.  Second-generation antipsychotic drugs and extrapyramidal side effects: a systematic review and meta-analysis of head-to-head comparisons.

Authors:  Christine Rummel-Kluge; Katja Komossa; Sandra Schwarz; Heike Hunger; Franziska Schmid; Werner Kissling; John M Davis; Stefan Leucht
Journal:  Schizophr Bull       Date:  2010-05-31       Impact factor: 9.306

9.  Efficacy and safety of long-acting risperidone in elderly patients with schizophrenia and schizoaffective disorder.

Authors:  Robert A Lasser; Cynthia A Bossie; Young Zhu; Georges Gharabawi; Mariëlle Eerdekens; Michael Davidson
Journal:  Int J Geriatr Psychiatry       Date:  2004-09       Impact factor: 3.485

10.  Long-term safety and efficacy of long-acting risperidone in elderly psychotic patients.

Authors:  Werner Kissling; Per Glue; Rossella Medori; Steve Simpson
Journal:  Hum Psychopharmacol       Date:  2007-12       Impact factor: 1.672

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  1 in total

Review 1.  [Diseases of the schizophrenia spectrum disorder in old age : Diagnostic and therapeutic challenges].

Authors:  Christian Jagsch; Alex Hofer
Journal:  Z Gerontol Geriatr       Date:  2018-08-14       Impact factor: 1.281

  1 in total

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