| Literature DB >> 27293088 |
N K Zenkov1, A V Chechushkov, P M Kozhin, N V Kandalintseva, G G Martinovich, E B Menshchikova.
Abstract
Many plant phenols (stilbenes, curcumins, catechins, flavonoids, etc.) are effective antioxidants and protect cells during oxidative stress. Extensive clinical studies on the potential of phenolic compounds for treatment of cardiovascular, neurodegenerative, oncological, and inflammatory diseases are now being conducted. In addition to direct antioxidant effect, plant phenols may provide a protective effect via activation of the Keap1/Nrf2/ARE redox-sensitive signaling system and regulation of autophagy. In this review, mechanisms of effects of the most common plant phenols on autophagy are presented.Entities:
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Year: 2016 PMID: 27293088 DOI: 10.1134/S0006297916040015
Source DB: PubMed Journal: Biochemistry (Mosc) ISSN: 0006-2979 Impact factor: 2.487