Literature DB >> 27291985

The Chemistry and Bio-Medicinal Significance of Pyrimidines & Condensed Pyrimidines.

K S Jain1, N Arya, N N Inamdar, P B Auti, S A Unawane, H H Puranik, M S Sanap, A D Inamke, V J Mahale, C S Prajapati, C J Shishoo.   

Abstract

This review discusses the biological and medicinal significance of one of the most important and interesting heterocyclic ring systems, the pyrimidine and its condensed derivatives. Herein, various physiologically important molecules, as well as, therapeutically used drugs having a pyrimidine or condensed pyrimidine system in their chemical structures, have been covered. The chemistry and synthesis of pyrimidines have also been briefly discussed.

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Year:  2016        PMID: 27291985     DOI: 10.2174/1568026616666160609100410

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN: 1568-0266            Impact factor:   3.295


  1 in total

1.  Design, Synthesis, Molecular Modeling and Antitumor Evaluation of Novel Indolyl-Pyrimidine Derivatives with EGFR Inhibitory Activity.

Authors:  Naglaa M Ahmed; Mahmoud M Youns; Moustafa K Soltan; Ahmed M Said
Journal:  Molecules       Date:  2021-03-25       Impact factor: 4.411

  1 in total

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