M Cuellar1, A W Harkrider2, D Jenson2, D Thornton2, A Bowers3, T Saltuklaroglu2. 1. Speech Language Pathology Program, Midwestern University, Downers Grove, IL, USA. Electronic address: mcuell@midwestern.edu. 2. Department of Audiology and Speech Pathology, University of Tennessee Health Science Center, Knoxville, TN, USA. 3. Department of Communication Disorders, University of Arkansas, Fayetteville, AR, USA.
Abstract
OBJECTIVE: Electroencephalography (EEG) was used to map the temporal dynamics of sensorimotor integration relative to the strength and timing of muscular activity during swallowing. METHODS: 64-channel EEG data and surface electromyographic (sEMG) data were recorded from 25 neurologically-healthy adults during swallowing and tongue-tapping. Events were demarcated so that sensorimotor activity primarily from the pharyngeal and esophageal phases of swallowing could be compared to activity resulting from tongue tapping. RESULTS: Independent component analysis identified bilateral clusters of sensorimotor mu components localized to the premotor and primary motor cortices as well as an infrahyoid myogenic cluster. Subsequent event-related spectral perturbations (ERSP) analyses showed event-related desynchronization (ERD) in the spectral power in the alpha (8-13Hz) and beta (15-25Hz) frequency bands of the mu clusters in both tasks. Mu ERD was stronger during swallowing when compared to tongue tapping (pFDR<.05) and the differences in sensorimotor processing between conditions was greater in the right hemisphere than the left, suggesting stronger right hemisphere lateralization for swallowing than tongue-tapping. CONCLUSION: Mu activity was interpreted as representing a normal feed forward and feedback driven sensorimotor loop during the later stages of swallowing. SIGNIFICANCE: Results support further use of this novel neuroimaging technique to concurrently map neural and muscle activity during swallowing in clinical populations using EEG.
OBJECTIVE: Electroencephalography (EEG) was used to map the temporal dynamics of sensorimotor integration relative to the strength and timing of muscular activity during swallowing. METHODS: 64-channel EEG data and surface electromyographic (sEMG) data were recorded from 25 neurologically-healthy adults during swallowing and tongue-tapping. Events were demarcated so that sensorimotor activity primarily from the pharyngeal and esophageal phases of swallowing could be compared to activity resulting from tongue tapping. RESULTS: Independent component analysis identified bilateral clusters of sensorimotor mu components localized to the premotor and primary motor cortices as well as an infrahyoid myogenic cluster. Subsequent event-related spectral perturbations (ERSP) analyses showed event-related desynchronization (ERD) in the spectral power in the alpha (8-13Hz) and beta (15-25Hz) frequency bands of the mu clusters in both tasks. Mu ERD was stronger during swallowing when compared to tongue tapping (pFDR<.05) and the differences in sensorimotor processing between conditions was greater in the right hemisphere than the left, suggesting stronger right hemisphere lateralization for swallowing than tongue-tapping. CONCLUSION: Mu activity was interpreted as representing a normal feed forward and feedback driven sensorimotor loop during the later stages of swallowing. SIGNIFICANCE: Results support further use of this novel neuroimaging technique to concurrently map neural and muscle activity during swallowing in clinical populations using EEG.
Authors: Tim Saltuklaroglu; Ashley W Harkrider; David Thornton; David Jenson; Tiffani Kittilstved Journal: Neuroimage Date: 2017-04-09 Impact factor: 6.556
Authors: Tiffani Kittilstved; Kevin J Reilly; Ashley W Harkrider; Devin Casenhiser; David Thornton; David E Jenson; Tricia Hedinger; Andrew L Bowers; Tim Saltuklaroglu Journal: Front Hum Neurosci Date: 2018-04-04 Impact factor: 3.169