Literature DB >> 2729166

Iron fortification of infant cereals: a proposal for the use of ferrous fumarate or ferrous succinate.

R F Hurrell1, D E Furniss, J Burri, P Whittaker, S R Lynch, J D Cook.   

Abstract

Hemoglobin-repletion tests in rats, organoleptic studies, and iron-absorption studies in humans were used to search for Fe sources with high bioavailability that could be added to infant cereals as alternatives to the Fe compounds currently used for fortification. From rat and organoleptic studies on 11 alternative Fe sources, ferrous fumarate, ferrous succinate, and ferric saccharate were selected as the most suitable for infant-cereal fortification and, by use of radioactive labels, absorption of those compounds from fortified cereal was measured in adult human volunteers. There was no difference in absorption between ferrous fumarate and ferrous sulfate whereas the values for ferrous succinate, ferrous saccharate (10% Fe), and ferric pyrophosphate were 92%, 74%, and 39% of the ferrous sulfate values, respectively. We conclude that ferrous fumarate and ferrous succinate are highly available Fe sources in man that can be used to fortify infant cereals without causing fat oxidation or discoloration.

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Year:  1989        PMID: 2729166     DOI: 10.1093/ajcn/49.6.1274

Source DB:  PubMed          Journal:  Am J Clin Nutr        ISSN: 0002-9165            Impact factor:   7.045


  8 in total

1.  Dry cereals fortified with electrolytic iron or ferrous fumarate are equally effective in breast-fed infants.

Authors:  Ekhard E Ziegler; Samuel J Fomon; Steven E Nelson; Janice M Jeter; Richard C Theuer
Journal:  J Nutr       Date:  2010-12-22       Impact factor: 4.798

2.  Iron Bioavailability from Ferrous Ammonium Phosphate, Ferrous Sulfate, and Ferric Pyrophosphate in an Instant Milk Drink-A Stable Isotope Study in Children.

Authors:  Richard F Hurrell; Trinidad P Trinidad; Aida C Mallillin; Rosario S Sagum; Jasmin Tajeri Foman; Qiaoji Li; Christophe Zeder; Peter Kastenmayer; Andreas Rytz; Magalie Sabatier; Ines Egli
Journal:  Nutrients       Date:  2022-04-14       Impact factor: 6.706

Review 3.  Ensuring the Efficacious Iron Fortification of Foods: A Tale of Two Barriers.

Authors:  Richard F Hurrell
Journal:  Nutrients       Date:  2022-04-12       Impact factor: 6.706

4.  Comparative study of the oral absorption of microencapsulated ferric saccharate and ferrous sulfate in humans.

Authors:  Carlos Contreras; María Dolores Barnuevo; Isabel Guillén; Antonio Luque; Elisabet Lázaro; Jordi Espadaler; Javier López-Román; José A Villegas
Journal:  Eur J Nutr       Date:  2013-07-27       Impact factor: 5.614

5.  Efficacy of iron fortification compared to iron supplementation among Vietnamese schoolchildren.

Authors:  Huong Thi Le; Inge D Brouwer; Jan Burema; Khan Cong Nguyen; Frans J Kok
Journal:  Nutr J       Date:  2006-12-05       Impact factor: 3.271

6.  High Bioavailability from Ferric Pyrophosphate-Fortified Bouillon Cubes in Meals is Not Increased by Sodium Pyrophosphate: a Stable Iron Isotope Study in Young Nigerian Women.

Authors:  Ans Eilander; Olumakaiye M Funke; Diego Moretti; Michael B Zimmermann; Temilola O Owojuyigbe; Cor Blonk; Peter Murray; Guus S Duchateau
Journal:  J Nutr       Date:  2019-05-01       Impact factor: 4.798

7.  The development of a novel ferric phytate compound for iron fortification of bouillons (part I).

Authors:  Swarnim Gupta; Edwin Habeych; Nathalie Scheers; Sylvie Merinat; Brigitte Rey; Nicola Galaffu; Ann-Sofie Sandberg
Journal:  Sci Rep       Date:  2020-03-24       Impact factor: 4.379

8.  Micronutrient-fortified infant cereal improves Hb status and reduces iron-deficiency anaemia in Indian infants: an effectiveness study.

Authors:  Shally Awasthi; Narayan U Reddy; Monjori Mitra; Shweta Singh; Sanjeev Ganguly; Ivana Jankovic; Dominik Grathwohl; Colin I Cercamondi; Apurba Ghosh
Journal:  Br J Nutr       Date:  2020-01-03       Impact factor: 3.718

  8 in total

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