Literature DB >> 27289479

Archaeogenetics in evolutionary medicine.

Abigail Bouwman1, Frank Rühli2.   

Abstract

Archaeogenetics is the study of exploration of ancient DNA (aDNA) of more than 70 years old. It is an important part of the wider studies of many different areas of our past, including animal, plant and pathogen evolution and domestication events. Hereby, we address specifically the impact of research in archaeogenetics in the broader field of evolutionary medicine. Studies on ancient hominid genomes help to understand even modern health patterns. Human genetic microevolution, e.g. related to abilities of post-weaning milk consumption, and specifically genetic adaptation in disease susceptibility, e.g. towards malaria and other infectious diseases, are of the upmost importance in contributions of archeogenetics on the evolutionary understanding of human health and disease. With the increase in both the understanding of modern medical genetics and the ability to deep sequence ancient genetic information, the field of archaeogenetic evolutionary medicine is blossoming.

Entities:  

Keywords:  Adaptive changes; Evolution of health; Immunity; Pathogen

Mesh:

Substances:

Year:  2016        PMID: 27289479     DOI: 10.1007/s00109-016-1438-8

Source DB:  PubMed          Journal:  J Mol Med (Berl)        ISSN: 0946-2716            Impact factor:   4.599


  56 in total

1.  Molecular evidence of HLA-B27 in a historical case of ankylosing spondylitis.

Authors:  Wolfgang Haak; Philipp Gruber; Frank J Rühli; Thomas Böni; Susi Ulrich-Bochsler; Elke Frauendorf; Joachim Burger; Kurt W Alt
Journal:  Arthritis Rheum       Date:  2005-10

2.  Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes.

Authors:  J C Stephens; D E Reich; D B Goldstein; H D Shin; M W Smith; M Carrington; C Winkler; G A Huttley; R Allikmets; L Schriml; B Gerrard; M Malasky; M D Ramos; S Morlot; M Tzetis; C Oddoux; F S di Giovine; G Nasioulas; D Chandler; M Aseev; M Hanson; L Kalaydjieva; D Glavac; P Gasparini; E Kanavakis; M Claustres; M Kambouris; H Ostrer; G Duff; V Baranov; H Sibul; A Metspalu; D Goldman; N Martin; D Duffy; J Schmidtke; X Estivill; S J O'Brien; M Dean
Journal:  Am J Hum Genet       Date:  1998-06       Impact factor: 11.025

3.  Nuclear DNA sequences from the Middle Pleistocene Sima de los Huesos hominins.

Authors:  Matthias Meyer; Juan-Luis Arsuaga; Cesare de Filippo; Sarah Nagel; Ayinuer Aximu-Petri; Birgit Nickel; Ignacio Martínez; Ana Gracia; José María Bermúdez de Castro; Eudald Carbonell; Bence Viola; Janet Kelso; Kay Prüfer; Svante Pääbo
Journal:  Nature       Date:  2016-03-14       Impact factor: 49.962

4.  Global distribution of the CCR5 gene 32-basepair deletion.

Authors:  J J Martinson; N H Chapman; D C Rees; Y T Liu; J B Clegg
Journal:  Nat Genet       Date:  1997-05       Impact factor: 38.330

5.  Historical variations in mutation rate in an epidemic pathogen, Yersinia pestis.

Authors:  Yujun Cui; Chang Yu; Yanfeng Yan; Dongfang Li; Yanjun Li; Thibaut Jombart; Lucy A Weinert; Zuyun Wang; Zhaobiao Guo; Lizhi Xu; Yujiang Zhang; Hancheng Zheng; Nan Qin; Xiao Xiao; Mingshou Wu; Xiaoyi Wang; Dongsheng Zhou; Zhizhen Qi; Zongmin Du; Honglong Wu; Xianwei Yang; Hongzhi Cao; Hu Wang; Jing Wang; Shusen Yao; Alexander Rakin; Yingrui Li; Daniel Falush; Francois Balloux; Mark Achtman; Yajun Song; Jun Wang; Ruifu Yang
Journal:  Proc Natl Acad Sci U S A       Date:  2012-12-27       Impact factor: 11.205

6.  Genotype of a historic strain of Mycobacterium tuberculosis.

Authors:  Abigail S Bouwman; Sandra L Kennedy; Romy Müller; Richard H Stephens; Malin Holst; Anwen C Caffell; Charlotte A Roberts; Terence A Brown
Journal:  Proc Natl Acad Sci U S A       Date:  2012-10-22       Impact factor: 11.205

7.  Distinct clones of Yersinia pestis caused the black death.

Authors:  Stephanie Haensch; Raffaella Bianucci; Michel Signoli; Minoarisoa Rajerison; Michael Schultz; Sacha Kacki; Marco Vermunt; Darlene A Weston; Derek Hurst; Mark Achtman; Elisabeth Carniel; Barbara Bramanti
Journal:  PLoS Pathog       Date:  2010-10-07       Impact factor: 6.823

8.  Absence of Yersinia pestis-specific DNA in human teeth from five European excavations of putative plague victims.

Authors:  M Thomas P Gilbert; Jon Cuccui; William White; Niels Lynnerup; Richard W Titball; Alan Cooper; Michael B Prentice
Journal:  Microbiology       Date:  2004-02       Impact factor: 2.777

9.  DNA sequence of the mitochondrial hypervariable region II from the neandertal type specimen.

Authors:  M Krings; H Geisert; R W Schmitz; H Krainitzki; S Pääbo
Journal:  Proc Natl Acad Sci U S A       Date:  1999-05-11       Impact factor: 11.205

10.  Evolutionary genetics: CCR5 mutation and plague protection.

Authors:  Joan Mecsas; Greg Franklin; William A Kuziel; Robert R Brubaker; Stanley Falkow; Donald E Mosier
Journal:  Nature       Date:  2004-02-12       Impact factor: 49.962

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