Jin-Seok Park1, Seok Jeong2,3, Byung Wook Bang1, Ae Ra Kang1, Don Haeng Lee4,5,6. 1. Department of Internal Medicine, Digestive Disease Center, Inha University Hospital, Inha University School of Medicine, 27 Inhang-ro, Jung-gu, Incheon, 400-711, South Korea. 2. Department of Internal Medicine, Digestive Disease Center, Inha University Hospital, Inha University School of Medicine, 27 Inhang-ro, Jung-gu, Incheon, 400-711, South Korea. inos@inha.ac.kr. 3. National Center of Efficacy Evaluation for the Development of Health Products Targeting Digestive Disorders (NCEED), Incheon, South Korea. inos@inha.ac.kr. 4. Department of Internal Medicine, Digestive Disease Center, Inha University Hospital, Inha University School of Medicine, 27 Inhang-ro, Jung-gu, Incheon, 400-711, South Korea. LDH@inha.ac.kr. 5. National Center of Efficacy Evaluation for the Development of Health Products Targeting Digestive Disorders (NCEED), Incheon, South Korea. LDH@inha.ac.kr. 6. Utah-Inha DDS and Advanced Therapeutics Research Center, Incheon, South Korea. LDH@inha.ac.kr.
Abstract
BACKGROUND: Endoscopic papillary large balloon dilatation (EPLBD) without endoscopic sphincterotomy (EST) is an accepted, simplified endoscopic technique for large common bile duct (CBD) stone removal. However, little is known about the long-term outcomes of this technique. The purpose of this study was to evaluate the long-term outcomes of EPLBD without EST for the treatment of large CBD stones. METHODS: This retrospective study of EPLBD without EST for a large CBD stone was conducted between June 2005 and October 2010. A total of 128 patients with a large CBD stone were included. The primary outcome measurement was complete CBD stone removal after EPLBD. Clinical data obtained from medical records were analyzed. RESULTS: The overall complete stone removal rate was 94.5 %. Mechanical lithotripsy was needed in 18 (14.1 %) patients. Post-procedural pancreatitis and asymptomatic hyperamylasemia occurred in 1 (0.8 %) and 11 (8.6 %) patients, respectively. One (0.8 %) patient experienced minor bleeding. The rate of stone recurrence was 13.1 %, and median time to stone recurrence was 600 days (range 144-2284 days). Over a half (64.3 %) of stone recurrences occurred during the 2 years following stone removal. Recurrence tended to be more frequent in patients with a large CBD diameter and in patients requiring multiple endoscopic sessions for complete CBD stone retrieval. CONCLUSION: EPLBD without EST may be safe and effective in patients with a large bile duct stone.
BACKGROUND: Endoscopic papillary large balloon dilatation (EPLBD) without endoscopic sphincterotomy (EST) is an accepted, simplified endoscopic technique for large common bile duct (CBD) stone removal. However, little is known about the long-term outcomes of this technique. The purpose of this study was to evaluate the long-term outcomes of EPLBD without EST for the treatment of large CBD stones. METHODS: This retrospective study of EPLBD without EST for a large CBD stone was conducted between June 2005 and October 2010. A total of 128 patients with a large CBD stone were included. The primary outcome measurement was complete CBD stone removal after EPLBD. Clinical data obtained from medical records were analyzed. RESULTS: The overall complete stone removal rate was 94.5 %. Mechanical lithotripsy was needed in 18 (14.1 %) patients. Post-procedural pancreatitis and asymptomatic hyperamylasemia occurred in 1 (0.8 %) and 11 (8.6 %) patients, respectively. One (0.8 %) patient experienced minor bleeding. The rate of stone recurrence was 13.1 %, and median time to stone recurrence was 600 days (range 144-2284 days). Over a half (64.3 %) of stone recurrences occurred during the 2 years following stone removal. Recurrence tended to be more frequent in patients with a large CBD diameter and in patients requiring multiple endoscopic sessions for complete CBD stone retrieval. CONCLUSION: EPLBD without EST may be safe and effective in patients with a large bile duct stone.
Entities:
Keywords:
Bile duct stone; Endoscopic papillary large balloon dilation; Endoscopic retrograde cholangiopancreatography; Long-term effect
Authors: Yoo Hum Baek; Hong Joo Kim; Jung Ho Park; Dong Il Park; Yong Kyun Cho; Chong Il Sohn; Woo Kyu Jeon; Byung Ik Kim Journal: Korean J Gastroenterol Date: 2009-07
Authors: J J Bergman; E A Rauws; P Fockens; A M van Berkel; P M Bossuyt; J G Tijssen; G N Tytgat; K Huibregtse Journal: Lancet Date: 1997-04-19 Impact factor: 79.321
Authors: Hyun Gun Kim; Young Koog Cheon; Young Deok Cho; Jong Ho Moon; Do Hyun Park; Tae Hoon Lee; Hyun Jong Choi; Sang-Heum Park; Joon Seong Lee; Moon Sung Lee Journal: World J Gastroenterol Date: 2009-09-14 Impact factor: 5.742