Literature DB >> 27286205

Inhibitory Effects of Ellagic Acid on Glucosyltransferases from Mutans Streptococci.

S Sawamura1,2, Y Tonosaki1, S Hamada1,2.   

Abstract

Ellagic acid and its derivatives were found to abrogate the enzymatic activity of the glucosyltransferases (GTases) of mutans streptococci. These compounds preferentially inhibited the water-soluble glucan synthesis by GTase of Streptococcus mutans MT8148 and inhibited the water-insoluble glucan synthesis by GTase of Streptococcus sobrinus 6715. This inhibition resulted in a reduction of cellular adherence of mutans streptococci to a glass surface.

Entities:  

Year:  1992        PMID： 27286205     DOI： 10.1271/bbb.56.766

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  3 in total

1.  New ellagitannins from Tiencha and their inhibitory activity against dental plaque.

Authors:  Fusako Nakano; Shozo Miyoshi; Toshiyuki Murakami
Journal:  J Nat Med       Date:  2017-04-28       Impact factor: 2.343

2.  Variation in total polyphenolics contents of aerial parts of Potentilla species and their anticariogenic activity.

Authors:  Michał Tomczyk; Małgorzata Pleszczyńska; Adrian Wiater
Journal:  Molecules       Date:  2010-06-29       Impact factor: 4.411

3.  In vitro activities of Acacia nilotica (L.) Delile bark fractions against Oral Bacteria, Glucosyltransferase and as antioxidant.

Authors:  Ali Mahmoud Muddathir; Ebtihal Abdalla M Mohieldin; Tohru Mitsunaga
Journal:  BMC Complement Med Ther       Date:  2020-11-23
  3 in total

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