Literature DB >> 27285108

Building up the tension between the epithelial and stromal compartment in pancreatic ductal adenocarcinoma.

G Biffi1, D Öhlund1, D Tuveson1.   

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Year:  2016        PMID: 27285108      PMCID: PMC4947673          DOI: 10.1038/cdd.2016.50

Source DB:  PubMed          Journal:  Cell Death Differ        ISSN: 1350-9047            Impact factor:   15.828


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  11 in total

1.  Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.

Authors:  Berna C Özdemir; Tsvetelina Pentcheva-Hoang; Julienne L Carstens; Xiaofeng Zheng; Chia-Chin Wu; Tyler R Simpson; Hanane Laklai; Hikaru Sugimoto; Christoph Kahlert; Sergey V Novitskiy; Ana De Jesus-Acosta; Padmanee Sharma; Pedram Heidari; Umar Mahmood; Lynda Chin; Harold L Moses; Valerie M Weaver; Anirban Maitra; James P Allison; Valerie S LeBleu; Raghu Kalluri
Journal:  Cancer Cell       Date:  2014-05-22       Impact factor: 31.743

2.  Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.

Authors:  Andrew D Rhim; Paul E Oberstein; Dafydd H Thomas; Emily T Mirek; Carmine F Palermo; Stephen A Sastra; Erin N Dekleva; Tyler Saunders; Claudia P Becerra; Ian W Tattersall; C Benedikt Westphalen; Jan Kitajewski; Maite G Fernandez-Barrena; Martin E Fernandez-Zapico; Christine Iacobuzio-Donahue; Kenneth P Olive; Ben Z Stanger
Journal:  Cancer Cell       Date:  2014-05-22       Impact factor: 31.743

3.  Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma.

Authors:  Paolo P Provenzano; Carlos Cuevas; Amy E Chang; Vikas K Goel; Daniel D Von Hoff; Sunil R Hingorani
Journal:  Cancer Cell       Date:  2012-03-20       Impact factor: 31.743

Review 4.  Stromal biology and therapy in pancreatic cancer.

Authors:  Albrecht Neesse; Patrick Michl; Kristopher K Frese; Christine Feig; Natalie Cook; Mike A Jacobetz; Martijn P Lolkema; Malte Buchholz; Kenneth P Olive; Thomas M Gress; David A Tuveson
Journal:  Gut       Date:  2010-10-21       Impact factor: 23.059

5.  STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis.

Authors:  Ryan B Corcoran; Gianmarco Contino; Vikram Deshpande; Alexandros Tzatsos; Claudius Conrad; Cyril H Benes; David E Levy; Jeffrey Settleman; Jeffrey A Engelman; Nabeel Bardeesy
Journal:  Cancer Res       Date:  2011-05-17       Impact factor: 12.701

6.  Tumor-stroma interaction of human pancreatic cancer: acquired resistance to anticancer drugs and proliferation regulation is dependent on extracellular matrix proteins.

Authors:  Hidenori Miyamoto; Tatsuya Murakami; Kunihiro Tsuchida; Hiromu Sugino; Hidenori Miyake; Seiki Tashiro
Journal:  Pancreas       Date:  2004-01       Impact factor: 3.327

7.  Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.

Authors:  Kenneth P Olive; Michael A Jacobetz; Christian J Davidson; Aarthi Gopinathan; Dominick McIntyre; Davina Honess; Basetti Madhu; Mae A Goldgraben; Meredith E Caldwell; David Allard; Kristopher K Frese; Gina Denicola; Christine Feig; Chelsea Combs; Stephen P Winter; Heather Ireland-Zecchini; Stefanie Reichelt; William J Howat; Alex Chang; Mousumi Dhara; Lifu Wang; Felix Rückert; Robert Grützmann; Christian Pilarsky; Kamel Izeradjene; Sunil R Hingorani; Pearl Huang; Susan E Davies; William Plunkett; Merrill Egorin; Ralph H Hruban; Nigel Whitebread; Karen McGovern; Julian Adams; Christine Iacobuzio-Donahue; John Griffiths; David A Tuveson
Journal:  Science       Date:  2009-05-21       Impact factor: 47.728

8.  Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.

Authors:  Hanane Laklai; Yekaterina A Miroshnikova; Michael W Pickup; Eric A Collisson; Grace E Kim; Alex S Barrett; Ryan C Hill; Johnathon N Lakins; David D Schlaepfer; Janna K Mouw; Valerie S LeBleu; Nilotpal Roy; Sergey V Novitskiy; Julia S Johansen; Valeria Poli; Raghu Kalluri; Christine A Iacobuzio-Donahue; Laura D Wood; Matthias Hebrok; Kirk Hansen; Harold L Moses; Valerie M Weaver
Journal:  Nat Med       Date:  2016-04-18       Impact factor: 53.440

9.  Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer.

Authors:  Christine Feig; James O Jones; Matthew Kraman; Richard J B Wells; Andrew Deonarine; Derek S Chan; Claire M Connell; Edward W Roberts; Qi Zhao; Otavia L Caballero; Sarah A Teichmann; Tobias Janowitz; Duncan I Jodrell; David A Tuveson; Douglas T Fearon
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-25       Impact factor: 11.205

Review 10.  Fibroblast heterogeneity in the cancer wound.

Authors:  Daniel Öhlund; Ela Elyada; David Tuveson
Journal:  J Exp Med       Date:  2014-07-28       Impact factor: 14.307

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  1 in total

1.  Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids.

Authors:  Brooke Schuster; Michael Junkin; Sara Saheb Kashaf; Isabel Romero-Calvo; Kori Kirby; Jonathan Matthews; Christopher R Weber; Andrey Rzhetsky; Kevin P White; Savaş Tay
Journal:  Nat Commun       Date:  2020-10-19       Impact factor: 14.919

  1 in total

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