Literature DB >> 27284433

Giant seminoma in an undescended testicle metastasizing to the neck and liver.

Kai-Min Guo1, Yang Liu2, Yan-Ping Zhong3, Hong-Liang Wang1.   

Abstract

Germ cell tumors account for 98% of all testicular malignancies. Delays in seeking treatment are unfortunately common and may lead to metastatic spread. The present study reported a case of a 24-year-old man with a giant 12×10 cm left inguinal mass and a left neck mass that had grown rapidly during recent months. Computed tomography confirmed that the mass measured 12.1×9.4 cm and was a left undescended testicle malignancy, and also revealed widespread metastasis to the liver and a large retroperitoneal mass (12.6×8.2 cm). Immunohistochemical staining confirmed seminoma. The patient was treated with chemotherapy with the VIP protocol (cisplatin, etoposide and ifosfamide). Following courses of chemotherapy, the patient received complete clinical remission and was disease-free at the 6 month follow-up.

Entities:  

Keywords:  chemotherapy; complete remission; cryptorchidism; late metastasis; seminoma

Year:  2016        PMID: 27284433      PMCID: PMC4887944          DOI: 10.3892/mco.2016.829

Source DB:  PubMed          Journal:  Mol Clin Oncol        ISSN: 2049-9450


  8 in total

1.  Twelve-year experience with two courses of adjuvant single-agent carboplatin therapy for clinical stage I seminoma.

Authors:  W J Reiter; T Brodowicz; S Alavi; C C Zielinski; W Kozak; U Maier; G Nöst; H Lipsky; M Marberger; C Kratzik
Journal:  J Clin Oncol       Date:  2001-01-01       Impact factor: 44.544

2.  SEOM clinical guidelines for diagnosis and treatment of testicular seminoma (2010).

Authors:  Jorge Aparicio; Javier Sastre; José Ramón Germà; Dolores Isla
Journal:  Clin Transl Oncol       Date:  2011-08       Impact factor: 3.405

Review 3.  Testicular germ cell tumors: pathogenesis, diagnosis and treatment.

Authors:  Christian Winter; Peter Albers
Journal:  Nat Rev Endocrinol       Date:  2010-11-30       Impact factor: 43.330

4.  Cervical lymph node dissection for metastatic testicular cancer.

Authors:  M G van Vledder; J A van der Hage; W J Kirkels; J W Oosterhuis; C Verhoef; J H W de Wilt
Journal:  Ann Surg Oncol       Date:  2010-03-24       Impact factor: 5.344

5.  Age at surgery for undescended testis and risk of testicular cancer.

Authors:  Andreas Pettersson; Lorenzo Richiardi; Agneta Nordenskjold; Magnus Kaijser; Olof Akre
Journal:  N Engl J Med       Date:  2007-05-03       Impact factor: 91.245

6.  Population based incidence and age distribution of spermatocytic seminoma.

Authors:  Philippe Carrière; Peter Baade; Lin Fritschi
Journal:  J Urol       Date:  2007-05-11       Impact factor: 7.450

7.  ERG expression is an independent prognostic factor and allows refined risk stratification in cytogenetically normal acute myeloid leukemia: a comprehensive analysis of ERG, MN1, and BAALC transcript levels using oligonucleotide microarrays.

Authors:  Klaus H Metzeler; Annika Dufour; Tobias Benthaus; Manuela Hummel; Maria-Cristina Sauerland; Achim Heinecke; Wolfgang E Berdel; Thomas Büchner; Bernhard Wörmann; Ulrich Mansmann; Jan Braess; Karsten Spiekermann; Wolfgang Hiddemann; Christian Buske; Stefan K Bohlander
Journal:  J Clin Oncol       Date:  2009-09-14       Impact factor: 44.544

8.  Diagnostic delay in oncology: a case report of metastatic seminoma.

Authors:  Norma Malavasi; Leonardo Ferrara; Claudia Fiorani; Alessia Saviola; Giuseppe Longo
Journal:  Case Rep Oncol       Date:  2011-04-06
  8 in total
  2 in total

1.  Large intra-abdominal seminoma in a left undescended testicle complicated by torsion.

Authors:  Elizabeth Rourke; Gilda Digman; Eric Gourley; Dharam Kaushik
Journal:  BMJ Case Rep       Date:  2018-03-28

2.  A metastasized hepatocellular carcinoma in the capsule of an undescended testis in the right inguinal area: report of a rare case.

Authors:  Qianhui Li; Xiuying Shi; Chuifeng Fan
Journal:  World J Surg Oncol       Date:  2018-01-19       Impact factor: 2.754

  2 in total

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