Literature DB >> 27284098

Park sleep: a non-motor dominant Parkinson's disease phenotype.

Carlo Canepa1.   

Abstract

A 69-year-old man was evaluated in our neurology department, for a presumed diagnosis of 'night-time seizures'; however, this diagnosis was quickly dismissed after the patient (and his wife) described how he 'acted out' and talked throughout his dreams, without any seizure-like activity. This problem had been present for ∼10 years. An EEG ruled out epilepsy. The patient also described a 10-year history of constipation, loss of smell and 'frequent collapses'. These symptoms fit in with the recently published criteria of 'prodromal Parkinson's Disease' and prompted a formal assessment for Parkinson's disease (PD). He had no tremor. A subtle festinating gait pattern and a 2-finger tremor in the right hand were noted. The diagnosis of PD was confirmed by a dopamine transporter scan. Clinically, this is one-Park sleep: rapid eye movement sleep behaviour disorder subtype-of 7 different non-motor dominant PD phenotypes recently described. 2016 BMJ Publishing Group Ltd.

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Year:  2016        PMID: 27284098      PMCID: PMC4904432          DOI: 10.1136/bcr-2016-215213

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  4 in total

1.  Reduced striatal dopamine transporters in idiopathic rapid eye movement sleep behaviour disorder. Comparison with Parkinson's disease and controls.

Authors:  I Eisensehr; R Linke; S Noachtar; J Schwarz; F J Gildehaus; K Tatsch
Journal:  Brain       Date:  2000-06       Impact factor: 13.501

2.  Staging of brain pathology related to sporadic Parkinson's disease.

Authors:  Heiko Braak; Kelly Del Tredici; Udo Rüb; Rob A I de Vos; Ernst N H Jansen Steur; Eva Braak
Journal:  Neurobiol Aging       Date:  2003 Mar-Apr       Impact factor: 4.673

Review 3.  Idiopathic REM sleep behavior disorder: toward a better nosologic definition.

Authors:  Maria Livia Fantini; Luigi Ferini-Strambi; Jacques Montplaisir
Journal:  Neurology       Date:  2005-03-08       Impact factor: 9.910

Review 4.  Non motor subtypes and Parkinson's disease.

Authors:  Anna Sauerbier; Peter Jenner; Antoniya Todorova; K Ray Chaudhuri
Journal:  Parkinsonism Relat Disord       Date:  2015-09-11       Impact factor: 4.891

  4 in total

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