Literature DB >> 27283434

Intelligent Albumin-MnO2 Nanoparticles as pH-/H2 O2 -Responsive Dissociable Nanocarriers to Modulate Tumor Hypoxia for Effective Combination Therapy.

Qian Chen1, Liangzhu Feng1, Jingjing Liu1, Wenwen Zhu1, Ziliang Dong1, Yifan Wu1, Zhuang Liu1.   

Abstract

A unique type of pH/H2 O2 dual-responsive intelligent nanoscale delivery system based on albumin-coated MnO2 is presented, which is capable of modulating the tumor microenvironment (TME) by relieving hypoxia. Additionally, TME-responsive size changes enable effective intratumor diffusion. A highly effective combined photodynamic and chemotherapy is realized with these nanoparticles in a mouse tumor model.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  albumin; combination therapies; deep penetration; manganese dioxide; tumor microenvironment

Year:  2016        PMID： 27283434     DOI： 10.1002/adma.201601902

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  115 in total

1.  A Porous Au@Rh Bimetallic Core-Shell Nanostructure as an H2 O2 -Driven Oxygenerator to Alleviate Tumor Hypoxia for Simultaneous Bimodal Imaging and Enhanced Photodynamic Therapy.

Authors:  Jinping Wang; Jingyu Sun; Wei Hu; Yuhao Wang; Tsengming Chou; Beilu Zhang; Qiang Zhang; Lei Ren; Hongjun Wang
Journal:  Adv Mater       Date:  2020-04-24       Impact factor: 30.849

2.  Manganese dioxide nanoparticles protect cartilage from inflammation-induced oxidative stress.

Authors:  Shreedevi Kumar; Isaac M Adjei; Shannon B Brown; Olivia Liseth; Blanka Sharma
Journal:  Biomaterials       Date:  2019-09-11       Impact factor: 12.479

3.  A Catalase-Like Metal-Organic Framework Nanohybrid for O2 -Evolving Synergistic Chemoradiotherapy.

Authors:  Zhimei He; Xiaolin Huang; Chen Wang; Xiangli Li; Yijing Liu; Zijian Zhou; Sheng Wang; Fuwu Zhang; Zhantong Wang; Orit Jacobson; Jun-Jie Zhu; Guocan Yu; Yunlu Dai; Xiaoyuan Chen
Journal:  Angew Chem Int Ed Engl       Date:  2019-05-16       Impact factor: 15.336

4.  The Use of Alternative Strategies for Enhanced Nanoparticle Delivery to Solid Tumors.

Authors:  Mukaddes Izci; Christy Maksoudian; Bella B Manshian; Stefaan J Soenen
Journal:  Chem Rev       Date:  2021-01-14       Impact factor: 60.622

Review 5.  Nanomaterial-Based Modulation of Tumor Microenvironments for Enhancing Chemo/Immunotherapy.

Authors:  Quoc-Viet Le; Juhan Suh; Yu-Kyoung Oh
Journal:  AAPS J       Date:  2019-05-17       Impact factor: 4.009

6.  H2O2-responsive liposomal nanoprobe for photoacoustic inflammation imaging and tumor theranostics via in vivo chromogenic assay.

Authors:  Qian Chen; Chao Liang; Xiaoqi Sun; Jiawen Chen; Zhijuan Yang; He Zhao; Liangzhu Feng; Zhuang Liu
Journal:  Proc Natl Acad Sci U S A       Date:  2017-05-08       Impact factor: 11.205

Review 7.  Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment.

Authors:  Yunlu Dai; Can Xu; Xiaolian Sun; Xiaoyuan Chen
Journal:  Chem Soc Rev       Date:  2017-05-18       Impact factor: 54.564

8.  A highly hemocompatible erythrocyte membrane-coated ultrasmall selenium nanosystem for simultaneous cancer radiosensitization and precise antiangiogenesis.

Authors:  Ting Liu; Changzheng Shi; Linqi Duan; Zehang Zhang; Liangping Luo; Shreya Goel; Weibo Cai; Tianfeng Chen
Journal:  J Mater Chem B       Date:  2018-06-29       Impact factor: 6.331

9.  Nanomedicine-Enabled Modulation of Tumor Hypoxic Microenvironment for Enhanced Cancer Therapy.

Authors:  Jinping Wang; Beilu Zhang; Jingyu Sun; Yuhao Wang; Hongjun Wang
Journal:  Adv Ther (Weinh)       Date:  2019-09-30

Review 10.  Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents.

Authors:  Dalong Ni; Wenbo Bu; Emily B Ehlerding; Weibo Cai; Jianlin Shi
Journal:  Chem Soc Rev       Date:  2017-11-27       Impact factor: 54.564
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